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MBD1 抗体 (C-Term)

This 兔 多克隆 antibody specifically detects MBD1 in WB 和 IHC. It exhibits reactivity toward 人, 大鼠, 犬, Cow, 豚鼠, 马 和 兔.
产品编号 ABIN2777532
发货至: 中国
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Quick Overview for MBD1 抗体 (C-Term) (ABIN2777532)

抗原

See all MBD1 抗体
MBD1 (Methyl-CpG Binding Domain Protein 1 (MBD1))

适用

  • 67
  • 19
  • 4
  • 4
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
人, 大鼠, 犬, Cow, 豚鼠, 马, 兔

宿主

  • 48
  • 20

克隆类型

  • 36
  • 32
多克隆

标记

  • 33
  • 4
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This MBD1 antibody is un-conjugated

应用范围

  • 48
  • 28
  • 18
  • 15
  • 13
  • 13
  • 12
  • 10
  • 10
  • 5
  • 3
  • 3
  • 1
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

    • 15
    • 6
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term

    序列

    EEDKEENKDD SASKLAPEEE AGGAGTPVIT EIFSLGGTRF RDTAVWLPRS

    预测反应

    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Rabbit: 100%, Rat: 100%

    产品特性

    This is a rabbit polyclonal antibody against MBD1. It was validated on Western Blot.

    纯化方法

    Affinity Purified
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 629 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    MBD1 (Methyl-CpG Binding Domain Protein 1 (MBD1))

    别名

    MBD1

    背景

    The protein encoded by this gene is a member of a family of nuclear proteins related by the presence of a methyl-CpG binding domain (MBD). These proteins are capable of binding specifically to methylated DNA, and some members can also repress transcription from methylated gene promoters. This protein contains multiple domains: MBD at the N-terminus that functions both in binding to methylated DNA and in protein interactions, several CXXC-type zinc finger domains that mediate binding to non-methylated CpG dinucleotides, transcriptional repression domain (TRD) at the C-terminus that is involved in transcription repression and in protein interactions. Numerous alternatively spliced transcript variants encoding different isoforms have been noted for this gene.
    Alias Symbols: CXXC3, PCM1, RFT
    Protein Interaction Partner: SUMO1, HTT, UBC, ECT2, APP, ATXN1L, TENM1, SUMO2, HIST1H3A, PCNA, ATF7IP2, ATF7IP, CHAF1A, SETDB1, PIAS1, STAT1, PRAM1, HDAC3, PIAS2, ZNF512B, Rnf2, CBX4, CBX5, HIPK3, SMAD9, OASL, SMAD5, SMAD3, SMAD7, SMAD1, SUV39H1,
    Protein Size: 629

    分子量

    69 kDa

    基因ID

    4152

    NCBI登录号

    NM_001204138, NP_001191067

    UniProt

    Q9UIS9
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