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FOXA2 抗体 (Middle Region)

This anti-FOXA2 antibody is a 兔 多克隆 antibody detecting FOXA2 in WB. Suitable for 人, 小鼠, 大鼠, 犬, 兔, 马 和 Pig. This Primary Antibody has been cited in 3+ publications.
产品编号 ABIN2777512
发货至: 中国

Quick Overview for FOXA2 抗体 (Middle Region) (ABIN2777512)

抗原

See all FOXA2 抗体
FOXA2 (Forkhead Box A2 (FOXA2))

适用

  • 84
  • 29
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  • 5
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  • 1
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人, 小鼠, 大鼠, 犬, 兔, 马, Pig

宿主

  • 80
  • 8
  • 2

克隆类型

  • 73
  • 17
多克隆

标记

  • 51
  • 5
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  • 3
  • 3
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  • 2
  • 2
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  • 1
  • 1
  • 1
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This FOXA2 antibody is un-conjugated

应用范围

  • 75
  • 37
  • 31
  • 20
  • 17
  • 14
  • 13
  • 11
  • 10
  • 7
  • 4
  • 2
  • 1
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Western Blotting (WB)
  • 抗原表位

    • 16
    • 9
    • 8
    • 8
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region

    序列

    ASQAQLGEAA GPASETPAGT ESPHSSASPC QEHKRGGLGE LKGTPAAALS

    预测反应

    Dog: 100%, Horse: 100%, Human: 100%, Mouse: 92%, Pig: 100%, Rabbit: 77%, Rat: 92%

    产品特性

    This is a rabbit polyclonal antibody against FOXA2. It was validated on Western Blot using a cell lysate as a positive control.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the middle region of human FOXA2
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 457 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Kallas, Pook, Trei, Maimets: "SOX2 Is Regulated Differently from NANOG and OCT4 in Human Embryonic Stem Cells during Early Differentiation Initiated with Sodium Butyrate." in: Stem cells international, Vol. 2014, pp. 298163, (2014) (PubMed).

    Menga, Infantino, Iacobazzi, Convertini, Palmieri, Iacobazzi: "Insight into mechanism of in vitro insulin secretion increase induced by antipsychotic clozapine: role of FOXA1 and mitochondrial citrate carrier." in: European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, Vol. 23, Issue 8, pp. 978-87, (2013) (PubMed).

    Richards, Park, Chen, Gibson, Peter Di, Pardo, Watkins, Choi, Selman, Pilewski, Kaminski, Zhang: "Allele-specific transactivation of matrix metalloproteinase 7 by FOXA2 and correlation with plasma levels in idiopathic pulmonary fibrosis." in: American journal of physiology. Lung cellular and molecular physiology, Vol. 302, Issue 8, pp. L746-54, (2012) (PubMed).

  • 抗原

    FOXA2 (Forkhead Box A2 (FOXA2))

    别名

    FOXA2

    背景

    FOXA2 is a member of the forkhead class of DNA-binding proteins. These hepatocyte nuclear factors are transcriptional activators for liver-specific transcripts such as albumin and transthyretin, and they also interact with chromatin. Similar family members in mice have roles in the regulation of metabolism and in the differentiation of the pancreas and liver. This gene has been linked to sporadic cases of maturity-onset diabetes of the young.This gene encodes a member of the forkhead class of DNA-binding proteins. These hepatocyte nuclear factors are transcriptional activators for liver-specific transcripts such as albumin and transthyretin, and they also interact with chromatin. Similar family members in mice have roles in the regulation of metabolism and in the differentiation of the pancreas and liver. This gene has been linked to sporadic cases of maturity-onset diabetes of the young. Two transcript variants encoding the same protein have been identified for this gene. This gene encodes a member of the forkhead class of DNA-binding proteins. These hepatocyte nuclear factors are transcriptional activators for liver-specific transcripts such as albumin and transthyretin, and they also interact with chromatin. Similar family members in mice have roles in the regulation of metabolism and in the differentiation of the pancreas and liver. This gene has been linked to sporadic cases of maturity-onset diabetes of the young. Two transcript variants encoding the same protein have been identified for this gene.
    Alias Symbols: HNF3B, MGC19807, TCF3B
    Protein Interaction Partner: PPARGC1B, GSC, EN2, OTX2, ONECUT1, NCOA1, TLE1, MIP, HOXA5, LHX1,
    Protein Size: 457

    分子量

    48 kDa

    基因ID

    3170

    NCBI登录号

    NM_021784, NP_068556

    UniProt

    Q9Y261

    途径

    Dopaminergic Neurogenesis, Regulation of Carbohydrate Metabolic Process
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