FOXA2 抗体 (Middle Region)
Quick Overview for FOXA2 抗体 (Middle Region) (ABIN2777512)
抗原
See all FOXA2 抗体适用
宿主
克隆类型
标记
应用范围
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                                            抗原表位
- Middle Region
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                                            序列
- ASQAQLGEAA GPASETPAGT ESPHSSASPC QEHKRGGLGE LKGTPAAALS
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                                            预测反应
- Dog: 100%, Horse: 100%, Human: 100%, Mouse: 92%, Pig: 100%, Rabbit: 77%, Rat: 92%
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                                            产品特性
- This is a rabbit polyclonal antibody against FOXA2. It was validated on Western Blot using a cell lysate as a positive control.
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                                            纯化方法
- Affinity Purified
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                                            免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human FOXA2
 
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                                            应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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                                            说明
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                        Antigen size: 457 AA 
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                                            限制
- 仅限研究用
 
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                                            状态
- Liquid
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                                            浓度
- Lot specific
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                                            缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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                                            储存液
- Sodium azide
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                                            注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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                                            注意事项
- Avoid repeated freeze-thaw cycles.
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                                            储存条件
- -20 °C
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                                            储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
 
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    - 
                                            : "SOX2 Is Regulated Differently from NANOG and OCT4 in Human Embryonic Stem Cells during Early Differentiation Initiated with Sodium Butyrate."    in: Stem cells international, Vol. 2014, pp. 298163, (2014)         (PubMed).        
 : "Insight into mechanism of in vitro insulin secretion increase induced by antipsychotic clozapine: role of FOXA1 and mitochondrial citrate carrier." in: European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, Vol. 23, Issue 8, pp. 978-87, (2013) (PubMed).
 : "Allele-specific transactivation of matrix metalloproteinase 7 by FOXA2 and correlation with plasma levels in idiopathic pulmonary fibrosis." in: American journal of physiology. Lung cellular and molecular physiology, Vol. 302, Issue 8, pp. L746-54, (2012) (PubMed).
 
 
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                                            : "SOX2 Is Regulated Differently from NANOG and OCT4 in Human Embryonic Stem Cells during Early Differentiation Initiated with Sodium Butyrate."    in: Stem cells international, Vol. 2014, pp. 298163, (2014)         (PubMed).        
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    - FOXA2 (Forkhead Box A2 (FOXA2))
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                                            别名
- FOXA2
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                                            背景
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                        FOXA2 is a member of the forkhead class of DNA-binding proteins. These hepatocyte nuclear factors are transcriptional activators for liver-specific transcripts such as albumin and transthyretin, and they also interact with chromatin. Similar family members in mice have roles in the regulation of metabolism and in the differentiation of the pancreas and liver. This gene has been linked to sporadic cases of maturity-onset diabetes of the young.This gene encodes a member of the forkhead class of DNA-binding proteins. These hepatocyte nuclear factors are transcriptional activators for liver-specific transcripts such as albumin and transthyretin, and they also interact with chromatin. Similar family members in mice have roles in the regulation of metabolism and in the differentiation of the pancreas and liver. This gene has been linked to sporadic cases of maturity-onset diabetes of the young. Two transcript variants encoding the same protein have been identified for this gene. This gene encodes a member of the forkhead class of DNA-binding proteins. These hepatocyte nuclear factors are transcriptional activators for liver-specific transcripts such as albumin and transthyretin, and they also interact with chromatin. Similar family members in mice have roles in the regulation of metabolism and in the differentiation of the pancreas and liver. This gene has been linked to sporadic cases of maturity-onset diabetes of the young. Two transcript variants encoding the same protein have been identified for this gene.
 Alias Symbols: HNF3B, MGC19807, TCF3B
 Protein Interaction Partner: PPARGC1B, GSC, EN2, OTX2, ONECUT1, NCOA1, TLE1, MIP, HOXA5, LHX1,
 Protein Size: 457
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                                            分子量
- 48 kDa
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                                            基因ID
- 3170
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                                            NCBI登录号
- NM_021784, NP_068556
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                                            UniProt
- Q9Y261
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                                            途径
- Dopaminergic Neurogenesis, Regulation of Carbohydrate Metabolic Process
 抗原
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