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RACGAP1 抗体 (N-Term)

The 兔 多克隆 anti-RACGAP1 antibody (ABIN2777488) specifically detects RACGAP1 in WB. The antibody is reactive with 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马 和 兔 samples.
产品编号 ABIN2777488
发货至: 中国
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Quick Overview for RACGAP1 抗体 (N-Term) (ABIN2777488)

抗原

See all RACGAP1 抗体
RACGAP1 (Rac GTPase Activating Protein 1 (RACGAP1))

适用

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人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔

宿主

  • 94
  • 4
  • 1
  • 1

克隆类型

  • 84
  • 16
多克隆

标记

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This RACGAP1 antibody is un-conjugated

应用范围

  • 87
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  • 22
  • 15
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  • 2
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Western Blotting (WB)
  • 抗原表位

    • 19
    • 15
    • 8
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    • 5
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    • 1
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    N-Term

    序列

    EILSEGNEVQ FIQLAKDFED FRKKWQRTDH ELGKYKDLLM KAETERSALD

    预测反应

    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 86%, Rabbit: 100%, Rat: 100%

    产品特性

    This is a rabbit polyclonal antibody against RACGAP1. It was validated on Western Blot using a cell lysate as a positive control.

    纯化方法

    Protein A purified

    免疫原

    The immunogen is a synthetic peptide directed towards the N terminal region of human RACGAP1
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 632 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    RACGAP1 (Rac GTPase Activating Protein 1 (RACGAP1))

    别名

    RACGAP1

    背景

    Rho GTPases control a variety of cellular processes. There are 3 subtypes of Rho GTPases in the Ras superfamily of small G proteins: RHO, RAC, and CDC42. GTPase-activating proteins (GAPs) bind activated forms of Rho GTPases and stimulate GTP hydrolysis. Through this catalytic function, Rho GAPs negatively regulate Rho-mediated signals. GAPs may also serve as effector molecules and play a role in signaling downstream of Rho and other Ras-like GTPases.
    Alias Symbols: CYK4, ID-GAP, HsCYK-4, MgcRacGAP
    Protein Interaction Partner: MORF4L1, UBC, FZR1, MPG, TXNDC11, MPRIP, TANK, KIF23, AURKB, PPP2R4, ECT2, CDK1, IKBKG, CUL1, SH3KBP1, Racgap1, Shcbp1, Cd2ap, YWHAG, YWHAB, PRC1, SH3RF1, SLC26A8, SLC16A10, PRSS23, CHN2, MAP3K4, RND2, MAP3K10, TUBG1, TUBA4A, VAV1, NRAS, GRB2, SFN,
    Protein Size: 632

    分子量

    71 kDa

    基因ID

    29127

    NCBI登录号

    NM_013277, NP_037409

    UniProt

    Q9H0H5

    途径

    Regulation of Actin Filament Polymerization, Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling, Signaling of Hepatocyte Growth Factor Receptor
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