RACGAP1 抗体 (N-Term)
Quick Overview for RACGAP1 抗体 (N-Term) (ABIN2777488)
抗原
See all RACGAP1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- EILSEGNEVQ FIQLAKDFED FRKKWQRTDH ELGKYKDLLM KAETERSALD
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预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 86%, Rabbit: 100%, Rat: 100%
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产品特性
- This is a rabbit polyclonal antibody against RACGAP1. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Protein A purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human RACGAP1
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 632 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- RACGAP1 (Rac GTPase Activating Protein 1 (RACGAP1))
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别名
- RACGAP1
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背景
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Rho GTPases control a variety of cellular processes. There are 3 subtypes of Rho GTPases in the Ras superfamily of small G proteins: RHO, RAC, and CDC42. GTPase-activating proteins (GAPs) bind activated forms of Rho GTPases and stimulate GTP hydrolysis. Through this catalytic function, Rho GAPs negatively regulate Rho-mediated signals. GAPs may also serve as effector molecules and play a role in signaling downstream of Rho and other Ras-like GTPases.
Alias Symbols: CYK4, ID-GAP, HsCYK-4, MgcRacGAP
Protein Interaction Partner: MORF4L1, UBC, FZR1, MPG, TXNDC11, MPRIP, TANK, KIF23, AURKB, PPP2R4, ECT2, CDK1, IKBKG, CUL1, SH3KBP1, Racgap1, Shcbp1, Cd2ap, YWHAG, YWHAB, PRC1, SH3RF1, SLC26A8, SLC16A10, PRSS23, CHN2, MAP3K4, RND2, MAP3K10, TUBG1, TUBA4A, VAV1, NRAS, GRB2, SFN,
Protein Size: 632 -
分子量
- 71 kDa
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基因ID
- 29127
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NCBI登录号
- NM_013277, NP_037409
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UniProt
- Q9H0H5
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途径
- Regulation of Actin Filament Polymerization, Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling, Signaling of Hepatocyte Growth Factor Receptor
抗原
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