DDIT3 抗体 (N-Term)
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Quick Overview for DDIT3 抗体 (N-Term) (ABIN2777369)
抗原
See all DDIT3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- SLPFSFGTLS SWELEAWYED LQEVLSSDEN GGTYVSPPGN EEEESKIFTT
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预测反应
- Cow: 86%, Dog: 86%, Goat: 86%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 86%, Rabbit: 93%, Rat: 92%, Sheep: 86%
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产品特性
- This is a rabbit polyclonal antibody against DDIT3. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N-terminal region of Human DDIT3
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeat freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- DDIT3 (DNA-Damage-Inducible Transcript 3 (DDIT3))
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别名
- DDIT3
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背景
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This gene encodes a member of the CCAAT/enhancer-binding protein (C/EBP) family of transcription factors. The protein functions as a dominant-negative inhibitor by forming heterodimers with other C/EBP members, such as C/EBP and LAP (liver activator protein), and preventing their DNA binding activity. The protein is implicated in adipogenesis and erythropoiesis, is activated by endoplasmic reticulum stress, and promotes apoptosis. Fusion of this gene and FUS on chromosome 16 or EWSR1 on chromosome 22 induced by translocation generates chimeric proteins in myxoid liposarcomas or Ewing sarcoma. Multiple alternatively spliced transcript variants encoding two isoforms with different length have been identified.
Protein Interaction Partner: CCDC153, ATPAF2, ZC3H14, TRIB3, C11orf30, BATF3, VPS37C, AMOTL2, HSD17B14, SNAPC5, HDAC5, HDAC6, TNFSF12, ZBTB25, UBC, LMO2, HDAC1, FOSL2, EP300, CEBPG, C14orf80, GIPC1, BATF, ATF4, PPIB, MAFF, CREB3, FOSL1, NFIL3, MAFG, JUNB, JUN, FOS, EPAS1, DDIT3, DBP,
Protein Size: 192 -
分子量
- 21 kDa
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基因ID
- 1649
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NCBI登录号
- NP_001181985
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UniProt
- F8VS99
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途径
- Regulation of Muscle Cell Differentiation, ER-Nucleus Signaling, Skeletal Muscle Fiber Development, Cell RedoxHomeostasis
抗原
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