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ATF6B 抗体 (Middle Region)

ATF6B 适用: 人, 小鼠, 大鼠, Pig, Cow, 马, 犬 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2777358
发货至: 中国
  • 抗原 See all ATF6B 抗体
    ATF6B (Activating Transcription Factor 6 beta (ATF6B))
    抗原表位
    • 15
    • 8
    • 7
    • 6
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Middle Region
    适用
    • 32
    • 28
    • 9
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠, Pig, Cow, 马, 犬
    宿主
    • 46
    • 1
    克隆类型
    • 46
    • 1
    多克隆
    标记
    • 16
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This ATF6B antibody is un-conjugated
    应用范围
    • 40
    • 23
    • 13
    • 13
    • 6
    • 4
    • 4
    • 3
    • 2
    • 1
    Western Blotting (WB)
    序列
    FNRTESLRLA DELSGWVQRH QRGRRKIPQR AQERQKSQPR KKSPPVKAVP
    预测反应
    Cow: 86%, Dog: 93%, Horse: 93%, Human: 100%, Mouse: 86%, Pig: 85%, Rat: 86%
    产品特性
    This is a rabbit polyclonal antibody against CREBL1. It was validated on Western Blot using a cell lysate as a positive control.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the middle region of human CREBL1
    Top Product
    Discover our top product ATF6B Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 703 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原
    ATF6B (Activating Transcription Factor 6 beta (ATF6B))
    别名
    CREBL1 (ATF6B 产品)
    别名
    CREBL1 antibody, CREB-RP antibody, G13 antibody, AA617266 antibody, ATF6beta antibody, Creb-rp antibody, Crebl1 antibody, activating transcription factor 6 beta antibody, cyclic AMP-dependent transcription factor ATF-6 beta antibody, ATF6B antibody, LOC745411 antibody, Atf6b antibody
    背景
    ATF6B(CREBL1) is a transcription factor in the unfolded protein response (UPR) pathway during ER stress. Either as a homodimer or as a heterodimer with ATF6-alpha, the protein binds to the ER stress response element, interacting with nuclear transcription factor Y to activate UPR target genes. ATF6B is normally found in the membrane of the endoplasmic reticulum, however, under ER stress, the N-terminal cytoplasmic domain is cleaved from the rest of the protein and translocates to the nucleus. Two transcript variants encoding different isoforms have been found for this gene.The protein encoded by this gene bears sequence similarity with the Creb/ATF subfamily of the bZip superfamily of transcription factors. It localizes to both the cytoplasm and the nucleus. The gene localizes to the major histocompatibility complex (MHC) class III region on chromosome 6. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
    Alias Symbols: CREB-RP, FLJ10066, G13, CREBL1
    Protein Interaction Partner: CREBZF, XBP1, ATF6B, CDK6, UBC, SUMO2, ATF6, NFYC, MBTPS1, PHOX2A, MBTPS2, NFYA, HCVgp1,
    Protein Size: 703
    分子量
    77 kDa
    基因ID
    1388
    NCBI登录号
    NM_004381, NP_004372
    UniProt
    Q99941
    途径
    Thyroid Hormone Synthesis, Myometrial Relaxation and Contraction
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