ATF6B 抗体 (Middle Region)
Quick Overview for ATF6B 抗体 (Middle Region) (ABIN2777358)
抗原
See all ATF6B 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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序列
- FNRTESLRLA DELSGWVQRH QRGRRKIPQR AQERQKSQPR KKSPPVKAVP
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预测反应
- Cow: 86%, Dog: 93%, Horse: 93%, Human: 100%, Mouse: 86%, Pig: 85%, Rat: 86%
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产品特性
- This is a rabbit polyclonal antibody against CREBL1. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human CREBL1
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anti-Activating Transcription Factor 6 beta (ATF6B) (AA 560-589) antibody
ATF6B 适用: 人, 小鼠, Hamster WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Activating Transcription Factor 6 beta (ATF6B) (AA 560-589), (C-Term) antibodyATF6B 适用: 人, 小鼠, Hamster WB, IHC (p) 宿主: 兔 Polyclonal RB25603 unconjugated
anti-Activating Transcription Factor 6 beta (ATF6B) (AA 2-88) antibodyATF6B 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 4D10 unconjugated
anti-Activating Transcription Factor 6 beta (ATF6B) (Internal Region) antibodyATF6B 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Activating Transcription Factor 6 beta (ATF6B) antibodyATF6B 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Activating Transcription Factor 6 beta (ATF6B) (N-Term) antibodyATF6B 适用: 人, 大鼠, Pig, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Activating Transcription Factor 6 beta (ATF6B) (AA 504-553) antibodyATF6B 适用: 人, Pig WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 703 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- ATF6B (Activating Transcription Factor 6 beta (ATF6B))
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别名
- CREBL1
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背景
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ATF6B(CREBL1) is a transcription factor in the unfolded protein response (UPR) pathway during ER stress. Either as a homodimer or as a heterodimer with ATF6-alpha, the protein binds to the ER stress response element, interacting with nuclear transcription factor Y to activate UPR target genes. ATF6B is normally found in the membrane of the endoplasmic reticulum, however, under ER stress, the N-terminal cytoplasmic domain is cleaved from the rest of the protein and translocates to the nucleus. Two transcript variants encoding different isoforms have been found for this gene.The protein encoded by this gene bears sequence similarity with the Creb/ATF subfamily of the bZip superfamily of transcription factors. It localizes to both the cytoplasm and the nucleus. The gene localizes to the major histocompatibility complex (MHC) class III region on chromosome 6. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: CREB-RP, FLJ10066, G13, CREBL1
Protein Interaction Partner: CREBZF, XBP1, ATF6B, CDK6, UBC, SUMO2, ATF6, NFYC, MBTPS1, PHOX2A, MBTPS2, NFYA, HCVgp1,
Protein Size: 703 -
分子量
- 77 kDa
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基因ID
- 1388
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NCBI登录号
- NM_004381, NP_004372
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UniProt
- Q99941
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途径
- Thyroid Hormone Synthesis, Myometrial Relaxation and Contraction
抗原
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