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RIPK3 抗体 (N-Term)

Cited in 1 publication. The 兔 多克隆 anti-RIPK3 antibody (ABIN2777333) specifically detects RIPK3 in WB 和 IHC. The antibody is reactive with 人, 小鼠, 大鼠, Cow, Pig, 马 和 犬 samples.
产品编号 ABIN2777333
发货至: 中国
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Quick Overview for RIPK3 抗体 (N-Term) (ABIN2777333)

抗原

See all RIPK3 抗体
RIPK3 (Receptor-Interacting serine-threonine Kinase 3 (RIPK3))

适用

人, 小鼠, 大鼠, Cow, Pig, 马, 犬

宿主

  • 80
  • 13

克隆类型

  • 79
  • 14
多克隆

标记

  • 54
  • 7
  • 6
  • 5
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This RIPK3 antibody is un-conjugated

应用范围

  • 81
  • 46
  • 36
  • 18
  • 14
  • 11
  • 9
  • 5
  • 4
  • 2
  • 1
Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

    • 8
    • 8
    • 7
    • 7
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term

    序列

    GGSQSGTGSG EPGGTLGYLA PELFVNVNRK ASTASDVYSF GILMWAVLAG

    预测反应

    Cow: 79%, Dog: 93%, Horse: 86%, Human: 100%, Mouse: 86%, Pig: 86%, Rat: 91%

    产品特性

    This is a rabbit polyclonal antibody against RIPK3. It was validated on Western Blot and immunohistochemistry.

    纯化方法

    Protein A purified

    免疫原

    The immunogen is a synthetic peptide directed towards the N terminal region of human RIPK3
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 518 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Lazrek, Goffard, Schanen, Karquel, Bocket, Lion, Devaux, Hedouin, Gosset, Hober: "Detection of hepatitis C virus antibodies and RNA among medicolegal autopsy cases in Northern France." in: Diagnostic microbiology and infectious disease, Vol. 55, Issue 1, pp. 55-8, (2006) (PubMed).

  • 抗原

    RIPK3 (Receptor-Interacting serine-threonine Kinase 3 (RIPK3))

    别名

    RIPK3

    背景

    RIPK3 is a member of the receptor-interacting protein (RIP) family of serine/threonine protein kinases, and contains a C-terminal domain unique from other RIP family members. The protein is predominantly localized to the cytoplasm, and can undergo nucleocytoplasmic shuttling dependent on novel nuclear localization and export signals. It is a component of the tumor necrosis factor (TNF) receptor-I signaling complex, and can induce apoptosis and weakly activate the NF-kappaB transcription factor.The product of this gene is a member of the receptor-interacting protein (RIP) family of serine/threonine protein kinases, and contains a C-terminal domain unique from other RIP family members. The encoded protein is predominantly localized to the cytoplasm, and can undergo nucleocytoplasmic shuttling dependent on novel nuclear localization and export signals. It is a component of the tumor necrosis factor (TNF) receptor-I signaling complex, and can induce apoptosis and weakly activate the NF-kappaB transcription factor.
    Alias Symbols: RIP3, RIP3 beta, RIP3 gamma
    Protein Interaction Partner: BMH1, RFX6, FADD, RIPK1, CASP8, INPP5K, CDC37, STIP1, PYGL, FKBP5, FKBP4, CTNND1, UBC, XIAP, BIRC3, BIRC2, TICAM1, TRAF2, TNFRSF1A,
    Protein Size: 518

    分子量

    57 kDa

    基因ID

    11035

    NCBI登录号

    NM_006871, NP_006862

    UniProt

    Q9Y572

    途径

    Activation of Innate immune Response, Toll-Like Receptors Cascades
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