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HDAC6 抗体 (N-Term)

This anti-HDAC6 antibody is a 兔 多克隆 antibody detecting HDAC6 in WB, IHC 和 ChIP. Suitable for 人, 小鼠, 大鼠, Pig, 兔, 犬, 豚鼠, Cow 和 马.
产品编号 ABIN2777306
发货至: 中国
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for HDAC6 抗体 (N-Term) (ABIN2777306)

抗原

See all HDAC6 抗体
HDAC6 (Histone Deacetylase 6 (HDAC6))

适用

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人, 小鼠, 大鼠, Pig, 兔, 犬, 豚鼠, Cow, 马

宿主

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  • 18
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克隆类型

  • 106
  • 36
多克隆

标记

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This HDAC6 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), Chromatin Immunoprecipitation (ChIP)
  • 抗原表位

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    N-Term

    序列

    VGLQGMDLNL EAEALAGTGL VLDEQLNEFH CLWDDSFPEG PERLHAIKEQ

    预测反应

    Cow: 93%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 86%, Pig: 100%, Rabbit: 100%, Rat: 93%

    产品特性

    This is a rabbit polyclonal antibody against HDAC6. It was validated on Western Blot using a cell lysate as a positive control.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the N terminal region of human HDAC6
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 1215 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    HDAC6 (Histone Deacetylase 6 (HDAC6))

    别名

    HDAC6

    背景

    Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein belongs to class II of the histone deacetylase/acuc/apha family. It contains an internal duplication of two catalytic domains which appear to function independently of each other. This protein possesses histone deacetylase activity and represses transcription.
    Alias Symbols: HD6, JM21
    Protein Interaction Partner: HSP90B1, ACTB, UBC, TRIM50, MYH10, DYNC1H1, DDIT3, ELAVL1, MAPK3, MAPK1, RUNX2, TUBA1B, SUMO1, RANBP9, NEDD8, ADRB2, ATXN3, MEF2B, SQSTM1, HSP90AA1, RASSF2, SLMAP, SAV1, CTTNBP2NL, BAG3, SETD8, TUBB, HSPA8, HSPA6, HSPA5, HSPA4, HSPA2, HSPA1L, DNAJA1, ETV6
    Protein Size: 1215

    分子量

    131 kDa, 17 kDa

    基因ID

    10013

    NCBI登录号

    NM_006044

    UniProt

    Q9UBN7

    途径

    Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling
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