CDK7 抗体 (N-Term)
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北京 101111
Quick Overview for CDK7 抗体 (N-Term) (ABIN2777258)
抗原
See all CDK7 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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原理
- CDK7 Antibody - N-terminal region
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序列
- VKSRAKRYEK LDFLGEGQFA TVYKARDKNT NQIVAIKKIK LGHRSEAKDG
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预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%
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产品特性
- This is a rabbit polyclonal antibody against CDK7. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N-terminal region of Human CDK7
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP31341-100UG
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 mg/mL
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缓冲液
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- prevent freeze-thaw cycles
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储存条件
- 4 °C,-20 °C
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储存方法
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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- CDK7 (Cyclin-Dependent Kinase 7 (CDK7))
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别名
- CDK7
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背景
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Background Information: CDK7 is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of Saccharomyces cerevisiae cdc28, and Schizosaccharomyces pombe cdc2, and are known to be important regulators of cell cycle progression. This protein forms a trimeric complex with cyclin H and MAT1, which functions as a Cdk-activating kinase (CAK). It is an essential component of the transcription factor TFIIH, that is involved in transcription initiation and DNA repair. This protein is thought to serve as a direct link between the regulation of transcription and the cell cycle.
Gene Name: cyclin-dependent kinase 7
Alternative Symbols: CAK, CAK1, HCAK, MO15, STK1, CDKN7, p39MO15
Protein Name: Cyclin-dependent kinase 7
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分子量
- 39kDa
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基因ID
- 1022
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NCBI登录号
- NP_001790
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UniProt
- P50613
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途径
- Cell Division Cycle, DNA Damage Repair, Intracellular Steroid Hormone Receptor Signaling Pathway, Mitotic G1-G1/S Phases, M Phase
抗原
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