Retinoic Acid Receptor beta 抗体 (N-Term)
Quick Overview for Retinoic Acid Receptor beta 抗体 (N-Term) (ABIN2777235)
抗原
See all Retinoic Acid Receptor beta (RARB) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- EKALKACFSG LTQTEWQHRH TAQSIETQST SSEELVPSPP SPLPPPRVYK
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预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 92%, Rabbit: 100%, Rat: 92%
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产品特性
- This is a rabbit polyclonal antibody against RARB. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N-terminal region of Human RARB
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeat freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Retinoic Acid Receptor beta (RARB) (Retinoic Acid Receptor, beta (RARB))
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别名
- RARB
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背景
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This gene encodes retinoic acid receptor beta, a member of the thyroid-steroid hormone receptor superfamily of nuclear transcriptional regulators. This receptor localizes to the cytoplasm and to subnuclear compartments. It binds retinoic acid, the biologically active form of vitamin A which mediates cellular signalling in embryonic morphogenesis, cell growth and differentiation. It is thought that this protein limits growth of many cell types by regulating gene expression. The gene was first identified in a hepatocellular carcinoma where it flanks a hepatitis B virus integration site. The gene expresses at least two transcript variants, one additional transcript has been described, but its full length nature has not been determined.
Protein Interaction Partner: RXRG, RXRB, MEOX2, ITGB1BP2, PRKD2, SMAD2, CCNH, HACE1, PNRC1, NCOR2, EIF3I, NCOA1, MAP6, SRC, RXRA, HR, GATA3, NCOA3, CEBPB, CEBPA, NR4A2, DNMT3B, DNMT3A, DNMT1, HIST4H4, HDAC1,
Protein Size: 448 -
分子量
- 49 kDa
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基因ID
- 5915
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途径
- Nuclear Receptor Transcription Pathway, Retinoic Acid Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway
抗原
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