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Androgen Receptor 抗体 (N-Term)

Name: Androgen Receptor 抗体 (N-Term)
SKU: ABIN2777192
Availability: OutOfStock

This anti-Androgen Receptor antibody is a 兔多克隆 antibody detecting Androgen Receptor in WB. Suitable for 人, 小鼠, 大鼠, Pig, 犬, Cow, 马, 兔, 豚鼠和绵羊.

WB Suggested Anti-AR Antibody Titration: 0. (Androgen Receptor 抗体 (N-Term))

Host: Rabbit Target Name: AR Sample Type: Human Fetal Lung Antibody Dilution: 1. (Androgen Receptor 抗体 (N-Term))

2 images

产品编号 ABIN2777192

发货至: 中国

Quick Overview for Androgen Receptor 抗体 (N-Term) (ABIN2777192)

抗原

See all Androgen Receptor (AR) 抗体

Androgen Receptor (AR)

适用

人, 小鼠, 大鼠, Pig, 犬, Cow, 马, 兔, 豚鼠, 绵羊

宿主

兔

克隆类型

多克隆

标记

This Androgen Receptor antibody is un-conjugated

应用范围

Western Blotting (WB)

Discover our top product AR Primary Antibody

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N-Term

序列

MEVQLGLGRV YPRPPSKTYR GAFQNLFQSV REVIQNPGPR HPEAASAAPP

预测反应

Cow: 86%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 93%, Pig: 100%, Rabbit: 86%, Rat: 93%, Sheep: 86%

产品特性

This is a rabbit polyclonal antibody against AR. It was validated on Western Blot using a cell lysate as a positive control.

纯化方法

Affinity Purified

免疫原

The immunogen is a synthetic peptide directed towards the N terminal region of human AR
anti-Androgen Receptor (AR) antibody
AR 适用: 人, 小鼠, 大鼠 WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Androgen Receptor (AR) (N-Term) antibody
AR 适用: 人 WB, IF, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated

anti-Androgen Receptor (AR) antibody
AR 适用: 人 WB, IHC, ELISA 宿主: 小鼠 Monoclonal 2H8 unconjugated

anti-Androgen Receptor (AR) antibody
AR 适用: 人, 小鼠, 大鼠, 猴 WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated

anti-Androgen Receptor (AR) (AA 491-679) antibody
AR 适用: 大鼠 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal C4 unconjugated

anti-Androgen Receptor (AR) (N-Term) antibody
Verified AR 适用: 人 WB, IHC, ELISA, IF, ChIP 宿主: 山羊 Polyclonal unconjugated

anti-Androgen Receptor (AR) (AA 221-320) antibody
AR 适用: 人 WB, ELISA, IHC (p), PLA 宿主: 小鼠 Monoclonal 1G3 unconjugated

anti-Androgen Receptor (AR) (AA 15-246) antibody
AR 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Androgen Receptor (AR) (AA 365-392) antibody
AR 适用: 人, 小鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated

anti-Androgen Receptor (AR) (AA 825-919) antibody
AR 适用: 人, 小鼠, 大鼠, Pig, 山羊 WB, ELISA, IHC (p), IF (p), IF (cc), IHC (fro) 宿主: 兔 Polyclonal unconjugated

应用备注

Optimal working dilutions should be determined experimentally by the investigator.

说明

Antigen size: 920 AA

限制

仅限研究用
状态

Liquid

浓度

Lot specific

缓冲液

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

Avoid repeated freeze-thaw cycles.

储存条件

-20 °C

储存方法

For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
抗原

Androgen Receptor (AR)

别名

AR

背景

AR has 3 major functional domains: the N-terminal domain, DNA-binding domain, and androgen-binding domain. The protein functions as a steroid-hormone activated transcription factor. Upon binding the hormone ligand, the receptor dissociates from accessory proteins, translocates into the nucleus, dimerizes, and then stimulates transcription of androgen responsive genes. This gene contains 2 polymorphic trinucleotide repeat segments that encode polyglutamine and polyglycine tracts in the N-terminal transactivation domain of its protein. Expansion of the polyglutamine tract causes spinal bulbar muscular atrophy (Kennedy disease). Mutations in this gene are also associated with complete androgen insensitivity (CAIS).The androgen receptor gene is more than 90 kb long and codes for a protein that has 3 major functional domains: the N-terminal domain, DNA-binding domain, and androgen-binding domain. The protein functions as a steroid-hormone activated transcription factor. Upon binding the hormone ligand, the receptor dissociates from accessory proteins, translocates into the nucleus, dimerizes, and then stimulates transcription of androgen responsive genes. This gene contains 2 polymorphic trinucleotide repeat segments that encode polyglutamine and polyglycine tracts in the N-terminal transactivation domain of its protein. Expansion of the polyglutamine tract causes spinal bulbar muscular atrophy (Kennedy disease). Mutations in this gene are also associated with complete androgen insensitivity (CAIS). Two alternatively spliced variants encoding distinct isoforms have been described.
Alias Symbols: AIS, DHTR, HUMARA, KD, NR3C4, SBMA, SMAX1, TFM, HYSP1
Protein Interaction Partner: AATF, SPOP, UBC, TSG101, TAF1, EP300, DAPK3, USP12, TTC5, SIRT1, RNF6, MAGEA11, VCP, KIF1A, NSD1, WIPI1, NDE1, NCOA1, REL, SMAD1, WDR77, AR, RANBP9, VHL, SKP2, RNF14, EZH2, BMI1, DCAF6, SUZ12, EED, RNF2, RBL1, PTGES3, NCOA4, SUMO2, CUL2, UXT, TCF4, ACTB,
Protein Size: 920

分子量

99 kDa

基因ID

367

NCBI登录号

NM_000044, NP_000035

UniProt

P10275

途径

Nuclear Receptor Transcription Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Nuclear Hormone Receptor Binding, Chromatin Binding