CBFB 抗体 (N-Term)
Quick Overview for CBFB 抗体 (N-Term) (ABIN2777178)
抗原
See all CBFB 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- MPRVVPDQRS KFENEEFFRK LSRECEIKYT GFRDRPHEER QARFQNACRD
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预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 79%, Horse: 79%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Yeast: 82%, Zebrafish: 100%
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产品特性
- This is a rabbit polyclonal antibody against CBFB. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N-terminal region of Human CBFB
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 182 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- CBFB (Core-Binding Factor, beta Subunit (CBFB))
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别名
- CBFB
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背景
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CBFB encodes a protein that is the beta subunit of a heterodimeric core-binding transcription factor belonging to the PEBP2/CBF transcription factor family which master-regulates a host of genes specific to hematopoiesis (e.g., RUNX1) and osteogenesis (e.g., RUNX2). The beta subunit is a non-DNA binding regulatory subunit, it allosterically enhances DNA binding by alpha subunit as the complex binds to the core site of various enhancers and promoters, including murine leukemia virus, polyomavirus enhancer, T-cell receptor enhancers and GM-CSF promoters.
Alias Symbols: PEBP2B
Protein Interaction Partner: vif, CUL5, UBC, RAB2A, MYC, nef, APOBEC3G, RUNX1, ELAVL1, KMT2A, COPRS, RUNX3, MYOD1, CHGB, CBFA2T2, RUNX2, CBFB, C1QBP,
Protein Size: 182 -
分子量
- 21 kDa
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基因ID
- 865
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NCBI登录号
- NM_001755, NP_001746
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UniProt
- Q13951
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途径
- Regulation of Lipid Metabolism by PPARalpha
抗原
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