PPL 抗体 (Middle Region)
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北京 101111
Quick Overview for PPL 抗体 (Middle Region) (ABIN2777127)
抗原
See all PPL 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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序列
- EKSRAQEKVT EKEVVKLQND PQLEAEYQQL QEDHQRQDQL REKQEEELSF
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预测反应
- Human: 100%, Pig: 82%
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产品特性
- This is a rabbit polyclonal antibody against PPL. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human PPL
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anti-Periplakin (PPL) (AA 1664-1701), (C-Term) antibody
PPL 适用: 人, 小鼠, 大鼠 WB, IHC, ICC, IF, FACS 宿主: 兔 Polyclonal unconjugated
anti-Periplakin (PPL) (AA 1664-1701) antibodyPPL 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Periplakin (PPL) (AA 1-130) antibodyPPL 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Periplakin (PPL) (AA 1501-1754) antibodyPPL 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Periplakin (PPL) antibodyPPL 适用: 人, 小鼠, 大鼠 WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated
anti-Periplakin (PPL) (AA 1-130) antibodyPPL 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Periplakin (PPL) antibodyPPL 适用: 人, 小鼠, 大鼠 IF 宿主: 兔 Polyclonal unconjugated
anti-Periplakin (PPL) (AA 1044-1093) antibodyPPL 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Periplakin (PPL) (AA 1439-1716) antibodyPPL 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Periplakin (PPL) (AA 1301-1330), (C-Term) antibodyPPL 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 1756 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- PPL (Periplakin (PPL))
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别名
- PPL
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背景
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PPL is a component of desmosomes and of the epidermal cornified envelope in keratinocytes. The N-terminal domain of this protein interacts with the plasma membrane and its C-terminus interacts with intermediate filaments. Through its rod domain, this protein forms complexes with envoplakin. This protein may serve as a link between the cornified envelope and desmosomes as well as intermediate filaments. AKT1/PKB, a protein kinase mediating a variety of cell growth and survival signaling processes, is reported to interact with this protein, suggesting a possible role for this protein as a localization signal in AKT1-mediated signaling.The protein encoded by this gene is a component of desmosomes and of the epidermal cornified envelope in keratinocytes. The N-terminal domain of this protein interacts with the plasma membrane and its C-terminus interacts with intermediate filaments. Through its rod domain, this protein forms complexes with envoplakin. This protein may serve as a link between the cornified envelope and desmosomes as well as intermediate filaments. AKT1/PKB, a protein kinase mediating a variety of cell growth and survival signaling processes, is reported to interact with this protein, suggesting a possible role for this protein as a localization signal in AKT1-mediated signaling. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: KIAA0568, MGC134872
Protein Interaction Partner: CEP57L1, ZSCAN1, RAB3IP, TSC22D4, RALBP1, AHCYL1, VIM, TRAF2, TRIM27, ALAS1, AKT1, SKIL, UBC, USP7, CUL1, ITSN1, Cdk1, KAZN, PPHLN1, EVPL, CASP6, OPRM1, COL17A1, KRT8, EZR,
Protein Size: 1756 -
分子量
- 205 kDa
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基因ID
- 5493
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NCBI登录号
- NM_002705, NP_002696
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UniProt
- O60437
抗原
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