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SERPINB5 抗体 (Middle Region)

This anti-SERPINB5 antibody is a 兔 多克隆 antibody detecting SERPINB5 in WB 和 IHC. Suitable for 人, 小鼠, 大鼠, 兔, Cow, 豚鼠, 犬 和 马. This Primary Antibody has been cited in 3+ publications.
产品编号 ABIN2777125
发货至: 中国

Quick Overview for SERPINB5 抗体 (Middle Region) (ABIN2777125)

抗原

See all SERPINB5 抗体
SERPINB5 (serpin Peptidase Inhibitor, Clade B (Ovalbumin), Member 5 (SERPINB5))

适用

人, 小鼠, 大鼠, 兔, Cow, 豚鼠, 犬, 马

宿主

  • 58
  • 10
  • 1

克隆类型

  • 58
  • 11
多克隆

标记

  • 41
  • 4
  • 4
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This SERPINB5 antibody is un-conjugated

应用范围

  • 62
  • 29
  • 27
  • 27
  • 19
  • 13
  • 13
  • 12
  • 10
  • 7
  • 6
  • 4
  • 2
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

    • 15
    • 7
    • 5
    • 5
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region

    序列

    NSVNDQTKIL VVNAAYFVGK WMKKFPESET KECPFRLNKT DTKPVQMMNM

    预测反应

    Cow: 86%, Dog: 93%, Guinea Pig: 86%, Horse: 93%, Human: 93%, Mouse: 86%, Rabbit: 86%, Rat: 93%

    产品特性

    This is a rabbit polyclonal antibody against SERPINB5. It was validated on Western Blot and immunohistochemistry.

    纯化方法

    Protein A purified

    免疫原

    The immunogen is a synthetic peptide directed towards the middle region of human SERPINB5
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 375 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Mardin, Ntalos, Mees, Spieker, Senninger, Haier, Dhayat: "SERPINB5 Promoter Hypomethylation Differentiates Pancreatic Ductal Adenocarcinoma From Pancreatitis." in: Pancreas, Vol. 45, Issue 5, pp. 743-7, (2016) (PubMed).

    Hrabakova, Kollareddy, Tyleckova, Halada, Hajduch, Gadher, Kovarova: "Cancer cell resistance to aurora kinase inhibitors: identification of novel targets for cancer therapy." in: Journal of proteome research, Vol. 12, Issue 1, pp. 455-69, (2013) (PubMed).

    Mardin, Petrov, Enns, Senninger, Haier, Mees: "SERPINB5 and AKAP12 - expression and promoter methylation of metastasis suppressor genes in pancreatic ductal adenocarcinoma." in: BMC cancer, Vol. 10, pp. 549, (2010) (PubMed).

  • 抗原

    SERPINB5 (serpin Peptidase Inhibitor, Clade B (Ovalbumin), Member 5 (SERPINB5))

    别名

    SERPINB5

    背景

    As a tumor suppressor, it blocks the growth, invasion, and metastatic properties of mammary tumors. As it does not undergo the S (stressed) to R (relaxed) conformational transition characteristic of active serpins, it exhibits no serine protease inhibitory activity.
    Alias Symbols: PI5, maspin
    Protein Interaction Partner: SUMO2, WWOX, FBXO32, KHDRBS3, ISG15, UBC, Cdk1, UCHL5, HDAC1,
    Protein Size: 375

    分子量

    41 kDa

    基因ID

    5268

    NCBI登录号

    NM_002639, NP_002630

    UniProt

    P36952

    途径

    p53 Pathway
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