FGF2 抗体 (Middle Region)
Quick Overview for FGF2 抗体 (Middle Region) (ABIN2777106)
抗原
See all FGF2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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序列
- RLESNNYNTY RSRKYTSWYV ALKRTGQYKL GSKTGPGQKA ILFLPMSAKS
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预测反应
- Cow: 93%, Dog: 93%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 93%, Zebrafish: 86%
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产品特性
- This is a rabbit polyclonal antibody against FGF2. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human FGF2
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anti-Fibroblast Growth Factor 2 (Basic) (FGF2) (AA 143-250) antibody
FGF2 适用: 人, 小鼠, 大鼠, 兔, 绵羊 WB, ELISA, FACS, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Fibroblast Growth Factor 2 (Basic) (FGF2) (AA 159-288) antibodyFGF2 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Fibroblast Growth Factor 2 (Basic) (FGF2) antibodyKO Validated FGF2 适用: 人 WB, IHC, IF 宿主: 兔 Monoclonal unconjugated
anti-Fibroblast Growth Factor 2 (Basic) (FGF2) (AA 26-153) antibody (APC)FGF2 适用: 兔 WB, IHC, IP, ICC 宿主: 豚鼠 Polyclonal APC
anti-Fibroblast Growth Factor 2 (Basic) (FGF2) (C-Term) antibodyFGF2 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Fibroblast Growth Factor 2 (Basic) (FGF2) (AA 189-288) antibodyFGF2 适用: 人 ELISA, FACS 宿主: 小鼠 Monoclonal 1A9B2 unconjugated
anti-Fibroblast Growth Factor 2 (Basic) (FGF2) (AA 143-288) antibodyFGF2 适用: 人 ELISA, ICC 宿主: 小鼠 Monoclonal 1D6B5 unconjugated
anti-Fibroblast Growth Factor 2 (Basic) (FGF2) (AA 143-288) antibodyFGF2 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Fibroblast Growth Factor 2 (Basic) (FGF2) antibodyFGF2 适用: 人 WB 宿主: 兔 Polyclonal RB52659 unconjugated
anti-Fibroblast Growth Factor 2 (Basic) (FGF2) (AA 10-155) antibodyFGF2 适用: 人 WB, ICC, IF 宿主: 小鼠 Monoclonal 2H11 unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 288 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- FGF2 (Fibroblast Growth Factor 2 (Basic) (FGF2))
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别名
- FGF2
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背景
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The heparin-binding growth factors are angiogenic agents in vivo and are potent mitogens for a variety of cell types in vitro. There are differences in the tissue distribution and concentration of these 2 growth factors.The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members bind heparin and possess broad mitogenic and angiogenic activities. This protein has been implicated in diverse biological processes, such as limb and nervous system development, wound healing, and tumor growth. The mRNA for this gene contains multiple polyadenylation sites, and is alternatively translated from non-AUG (CUG) and AUG initiation codons, resulting in five different isoforms with distinct properties. The CUG-initiated isoforms are localized in the nucleus and are responsible for the intracrine effect, whereas, the AUG-initiated form is mostly cytosolic and is responsible for the paracrine and autocrine effects of this FGF. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: BFGF, FGFB, HBGF-2
Protein Interaction Partner: TUBG1, HMT1, PRMT1, CRYAB, THBS1, UBC, API5, CEP57, FGFRL1, FGFBP1, CXCL13, RPL6, RPS19, PTX3, NRP1, GPC4, RPS6KA3, GPC3, VTN, SDC3, SDC1, PF4, HSPG2, SDC2, FGFR1, FGFR4, FGFR3, FGF2, CSNK2A2, CSNK2B, CSNK2A1, CD44, SDC4,
Protein Size: 288 -
分子量
- 31 kDa
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基因ID
- 2247
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NCBI登录号
- NM_002006, NP_001997
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UniProt
- P09038
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途径
- RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, C21-Steroid Hormone Metabolic Process, Inositol Metabolic Process, Glycosaminoglycan Metabolic Process, Protein targeting to Nucleus, S100 Proteins
抗原
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