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DAB2 抗体 (N-Term)

DAB2 适用: 人, 小鼠, 大鼠, 犬, 豚鼠, 兔, Cow WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2777076
发货至: 中国
  • 抗原 See all DAB2 抗体
    DAB2 (Disabled Homolog 2, Mitogen-Responsive phosphoprotein (Drosophila) (DAB2))
    抗原表位
    • 16
    • 15
    • 13
    • 13
    • 8
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    适用
    • 48
    • 32
    • 19
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠, 犬, 豚鼠, 兔, Cow
    宿主
    • 63
    • 12
    • 1
    克隆类型
    • 66
    • 10
    多克隆
    标记
    • 20
    • 7
    • 6
    • 6
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    This DAB2 antibody is un-conjugated
    应用范围
    • 68
    • 34
    • 26
    • 26
    • 18
    • 8
    • 6
    • 4
    • 4
    • 3
    • 2
    Western Blotting (WB)
    序列
    EVETSATNGQ PDQQAAPKAP SKKEKKKGPE KTDEYLLARF KGDGVKYKAK
    预测反应
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%
    产品特性
    This is a rabbit polyclonal antibody against DAB2. It was validated on Western Blot.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the N-terminal region of Human DAB2
    Top Product
    Discover our top product DAB2 Primary Antibody
  • 限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeat freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原
    DAB2 (Disabled Homolog 2, Mitogen-Responsive phosphoprotein (Drosophila) (DAB2))
    别名
    DAB2 (DAB2 产品)
    别名
    DOC-2 antibody, DOC2 antibody, 5730435J12Rik antibody, AA960054 antibody, AI957090 antibody, D15Wsu122e antibody, D630005B22Rik antibody, Doc-2 antibody, Doc2 antibody, p96 antibody, DAB2, clathrin adaptor protein antibody, disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila) antibody, Dab, mitogen-responsive phosphoprotein, homolog 2 antibody, disabled 2, mitogen-responsive phosphoprotein antibody, DAB2 antibody, dab2 antibody, Dab2 antibody
    背景
    This gene encodes a mitogen-responsive phosphoprotein. It is expressed in normal ovarian epithelial cells, but is down-regulated or absent from ovarian carcinoma cell lines, suggesting its role as a tumor suppressor. This protein binds to the SH3 domains of GRB2, an adaptor protein that couples tyrosine kinase receptors to SOS (a guanine nucleotide exchange factor for Ras), via its C-terminal proline-rich sequences, and may thus modulate growth factor/Ras pathways by competing with SOS for binding to GRB2. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
    Protein Interaction Partner: Fcho2, CPSF7, SMURF2, YLPM1, C14orf166, ACOT9, CPSF6, SF3B2, MALT1, HSPH1, SEC23B, SEC24B, NUP155, CDC16, TRIO, TFAP2A, AURKA, PYCR1, PRDX1, MYO6, HSPA1B, HNRNPL, GRB2, FN1, CLTC, AP2M1, CFTR, CCNT1, ACTB, AHCY, AP2B1, AP2A2, AP2A1, DYT10, ATXN1L, SH3KBP1
    Protein Size: 552
    分子量
    60 kDa
    基因ID
    1601
    途径
    Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process
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