DAB2 抗体 (N-Term)
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北京 101111
Quick Overview for DAB2 抗体 (N-Term) (ABIN2777076)
抗原
See all DAB2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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原理
- DAB2 Antibody - N-terminal region
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序列
- EVETSATNGQ PDQQAAPKAP SKKEKKKGPE KTDEYLLARF KGDGVKYKAK
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预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%
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产品特性
- This is a rabbit polyclonal antibody against DAB2. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N-terminal region of Human DAB2
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anti-Disabled Homolog 2, Mitogen-Responsive phosphoprotein (Drosophila) (DAB2) (AA 1-770) antibody
DAB2 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Disabled Homolog 2, Mitogen-Responsive phosphoprotein (Drosophila) (DAB2) (AA 743-770), (C-Term) antibodyDAB2 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB23472 unconjugated
anti-Disabled Homolog 2, Mitogen-Responsive phosphoprotein (Drosophila) (DAB2) (C-Term) antibodyDAB2 适用: 人, 小鼠, 大鼠 WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Disabled Homolog 2, Mitogen-Responsive phosphoprotein (Drosophila) (DAB2) antibodyKD Validated DAB2 适用: 人 WB, FACS 宿主: 兔 Monoclonal 25GB225 unconjugated Recombinant Antibody
anti-Disabled Homolog 2, Mitogen-Responsive phosphoprotein (Drosophila) (DAB2) (AA 89-770) antibodyDAB2 适用: 人, 小鼠, 大鼠, 猴 WB, ELISA, IHC, FACS, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Disabled Homolog 2, Mitogen-Responsive phosphoprotein (Drosophila) (DAB2) (AA 31-130) antibodyDAB2 适用: 人 WB, FACS, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Disabled Homolog 2, Mitogen-Responsive phosphoprotein (Drosophila) (DAB2) (AA 624-650), (C-Term) antibodyDAB2 适用: 小鼠 WB 宿主: 兔 Polyclonal RB40861 unconjugated
anti-Disabled Homolog 2, Mitogen-Responsive phosphoprotein (Drosophila) (DAB2) (pSer24) antibodyDAB2 适用: 人 WB, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Disabled Homolog 2, Mitogen-Responsive phosphoprotein (Drosophila) (DAB2) (AA 743-770) antibodyDAB2 适用: 人 WB, IHC, FACS, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Disabled Homolog 2, Mitogen-Responsive phosphoprotein (Drosophila) (DAB2) (AA 275-325) antibodyDAB2 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP41937-100UG
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 mg/mL
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缓冲液
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- prevent freeze-thaw cycles
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储存条件
- 4 °C,-20 °C
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储存方法
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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- DAB2 (Disabled Homolog 2, Mitogen-Responsive phosphoprotein (Drosophila) (DAB2))
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别名
- DAB2
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背景
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Background Information: This gene encodes a mitogen-responsive phosphoprotein. It is expressed in normal ovarian epithelial cells, but is down-regulated or absent from ovarian carcinoma cell lines, suggesting its role as a tumor suppressor. This protein binds to the SH3 domains of GRB2, an adaptor protein that couples tyrosine kinase receptors to SOS (a guanine nucleotide exchange factor for Ras), via its C-terminal proline-rich sequences, and may thus modulate growth factor/Ras pathways by competing with SOS for binding to GRB2. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Gene Name: disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)
Alternative Symbols: DOC2, DOC-2
Protein Name: Disabled homolog 2
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分子量
- 60kDa
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基因ID
- 1601
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UniProt
- P98082
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途径
- Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process
抗原
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