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C4B 抗体 (N-Term)

C4b 适用: 人, 小鼠, 马, 豚鼠, Pig, 大鼠, 犬 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2777022
发货至: 中国
  • 抗原 See all C4B (C4b) 抗体
    C4B (C4b) (Complement Component C4b (C4b))
    抗原表位
    • 15
    • 7
    • 6
    • 6
    • 6
    • 5
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    适用
    人, 小鼠, 马, 豚鼠, Pig, 大鼠, 犬
    宿主
    • 49
    • 5
    • 3
    克隆类型
    • 52
    • 5
    多克隆
    标记
    • 19
    • 8
    • 8
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This C4B antibody is un-conjugated
    应用范围
    • 29
    • 24
    • 14
    • 13
    • 13
    • 8
    • 7
    • 6
    • 6
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB)
    序列
    QTDQPIYNPG QRVRYRVFAL DQKMRPSTDT ITVMVENSHG LRVRKKEVYM
    预测反应
    Dog: 92%, Guinea Pig: 92%, Horse: 100%, Human: 100%, Mouse: 79%, Pig: 93%, Rat: 93%
    产品特性
    This is a rabbit polyclonal antibody against C4B. It was validated on Western Blot using a cell lysate as a positive control.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the N terminal region of human C4B
    Top Product
    Discover our top product C4b Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 1744 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原
    C4B (C4b) (Complement Component C4b (C4b))
    别名
    C4B (C4b 产品)
    别名
    C4B1 antibody, C4B12 antibody, C4B2 antibody, C4B3 antibody, C4B5 antibody, C4BD antibody, C4B_2 antibody, C4F antibody, CH antibody, CO4 antibody, CPAMD3 antibody, C4 antibody, C4A2 antibody, C4A3 antibody, C4A4 antibody, C4A6 antibody, C4AD antibody, C4S antibody, CPAMD2 antibody, RG antibody, wu:fi14a03 antibody, C4B antibody, DKFZP469I0332 antibody, Slp antibody, Ss antibody, C4-2 antibody, C4l antibody, complement C4B (Chido blood group) antibody, complement C4A (Rodgers blood group) antibody, complement component 4 antibody, complement C4-B antibody, complement component 4B (Chido blood group) antibody, complement component 4A (Rodgers blood group) antibody, C4B antibody, C4A antibody, c4 antibody, LOC462577 antibody, C4a antibody, C4b antibody
    背景
    C4B is the basic form of complement factor 4, part of the classical activation pathway. The protein is expressed as a single chain precursor which is proteolytically cleaved into a trimer of alpha, beta, and gamma chains prior to secretion. The trimer provides a surface for interaction between the antigen-antibody complex and other complement components. The alpha chain may be cleaved to release C4 anaphylatoxin, a mediator of local inflammation. Deficiency of this protein is associated with systemic lupus erythematosus. This gene encodes the basic form of complement factor 4, part of the classical activation pathway. The protein is expressed as a single chain precursor which is proteolytically cleaved into a trimer of alpha, beta, and gamma chains prior to secretion. The trimer provides a surface for interaction between the antigen-antibody complex and other complement components. The alpha chain may be cleaved to release C4 anaphylatoxin, a mediator of local inflammation. Deficiency of this protein is associated with systemic lupus erythematosus. This gene localizes to the major histocompatibility complex (MHC) class III region on chromosome 6. Varying haplotypes of this gene cluster exist, such that individuals may have 1, 2, or 3 copies of this gene. In addition, this gene exists as a long form and a short form due to the presence or absence of a 6.4 kb endogenous HERV-K retrovirus in intron 9. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
    Alias Symbols: C4A, C4A13, C4A91, C4B1, C4B12, C4B2, C4B3, C4B5, C4F, CH, CO4, CPAMD3, MGC164979
    Protein Size: 1744
    分子量
    193 kDa
    基因ID
    432395
    NCBI登录号
    NM_001002029, NP_001002029
    UniProt
    Q6U2E9
    途径
    Complement System
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