C4B 抗体 (N-Term)
Quick Overview for C4B 抗体 (N-Term) (ABIN2777022)
抗原
See all C4B (C4b) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- QTDQPIYNPG QRVRYRVFAL DQKMRPSTDT ITVMVENSHG LRVRKKEVYM
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预测反应
- Dog: 92%, Guinea Pig: 92%, Horse: 100%, Human: 100%, Mouse: 79%, Pig: 93%, Rat: 93%
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产品特性
- This is a rabbit polyclonal antibody against C4B. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human C4B
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anti-Complement Component C4b (C4b) (AA 126-366) antibody
C4b 适用: 小鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Complement Component C4b (C4b) (AA 680-756) antibodyC4b 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Complement Component C4b (C4b) (AA 1347-1446) antibodyC4b 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 1F2 unconjugated
anti-Complement Component C4b (C4b) (AA 19-333) antibodyC4b 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Complement Component C4b (C4b) (AA 1454-1744) antibodyC4b 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Complement Component C4b (C4b) antibodyC4b 适用: 人 IHC, IF, StM 宿主: 小鼠 Monoclonal SPM545 unconjugated
anti-Complement Component C4b (C4b) (AA 144-193) antibodyC4b 适用: 人, 小鼠, 马, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Complement Component C4b (C4b) (AA 655-684) antibodyC4b 适用: 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 1744 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- C4B (C4b) (Complement Component C4b (C4b))
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别名
- C4B
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背景
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C4B is the basic form of complement factor 4, part of the classical activation pathway. The protein is expressed as a single chain precursor which is proteolytically cleaved into a trimer of alpha, beta, and gamma chains prior to secretion. The trimer provides a surface for interaction between the antigen-antibody complex and other complement components. The alpha chain may be cleaved to release C4 anaphylatoxin, a mediator of local inflammation. Deficiency of this protein is associated with systemic lupus erythematosus. This gene encodes the basic form of complement factor 4, part of the classical activation pathway. The protein is expressed as a single chain precursor which is proteolytically cleaved into a trimer of alpha, beta, and gamma chains prior to secretion. The trimer provides a surface for interaction between the antigen-antibody complex and other complement components. The alpha chain may be cleaved to release C4 anaphylatoxin, a mediator of local inflammation. Deficiency of this protein is associated with systemic lupus erythematosus. This gene localizes to the major histocompatibility complex (MHC) class III region on chromosome 6. Varying haplotypes of this gene cluster exist, such that individuals may have 1, 2, or 3 copies of this gene. In addition, this gene exists as a long form and a short form due to the presence or absence of a 6.4 kb endogenous HERV-K retrovirus in intron 9. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: C4A, C4A13, C4A91, C4B1, C4B12, C4B2, C4B3, C4B5, C4F, CH, CO4, CPAMD3, MGC164979
Protein Size: 1744 -
分子量
- 193 kDa
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基因ID
- 432395
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NCBI登录号
- NM_001002029, NP_001002029
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UniProt
- Q6U2E9
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途径
- Complement System
抗原
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