Prothrombin 抗体 (Middle Region)
Quick Overview for Prothrombin 抗体 (Middle Region) (ABIN2776976)
抗原
See all Prothrombin (F2) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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序列
- ISDRWVLTAA HCLLYPPWDK NFTENDLLVR IGKHSRTRYE RNIEKISMLE
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预测反应
- Cow: 92%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rat: 100%, Sheep: 93%, Zebrafish: 77%
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产品特性
- This is a rabbit polyclonal antibody against F2. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human F2
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anti-Coagulation Factor II (thrombin) (F2) (AA 263-362) antibody
F2 适用: 人 WB, IP, ELISA, RNAi, PLA 宿主: 小鼠 Monoclonal 1B7 unconjugated
anti-Coagulation Factor II (thrombin) (F2) (AA 324-617) antibodyF2 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Coagulation Factor II (thrombin) (F2) (AA 44-200) antibodyF2 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Coagulation Factor II (thrombin) (F2) antibodyF2 适用: 人 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal E1 unconjugated
anti-Coagulation Factor II (thrombin) (F2) (AA 44-200) antibodyF2 适用: 大鼠 WB 宿主: 小鼠 Monoclonal C10 unconjugated
anti-Coagulation Factor II (thrombin) (F2) (Internal Region) antibodyF2 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Coagulation Factor II (thrombin) (F2) (AA 1-622) antibodyF2 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Coagulation Factor II (thrombin) (F2) (N-Term) antibodyF2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Coagulation Factor II (thrombin) (F2) (AA 67-124) antibodyF2 适用: 人 WB, IHC, ICC, ELISA, FACS 宿主: 兔 Polyclonal unconjugated
anti-Coagulation Factor II (thrombin) (F2) (AA 201-323) antibodyF2 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 622 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Prothrombin (F2) (Coagulation Factor II (thrombin) (F2))
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别名
- F2
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背景
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Coagulation factor II is proteolytically cleaved to form thrombin in the first step of the coagulation cascade which ultimately results in the stemming of blood loss. F2 also plays a role in maintaining vascular integrity during development and postnatal life.Coagulation factor II is proteolytically cleaved to form thrombin in the first step of the coagulation cascade which ultimately results in the stemming of blood loss. F2 also plays a role in maintaining vascular integrity during development and postnatal life. Mutations in F2 leads to various forms of thrombosis and dysprothrombinemia. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: PT
Protein Interaction Partner: ST13, FN1, DDIT3, ALB, F11, PROZ, ITGA2B, SERPING1, HGFAC, AKR7A2, CPB2, F2RL3, F2RL2, SERPINA5, SERPINB8, AANAT, F2RL1, F9, F8, GP1BA, KNG1, F5, C6, PLAU, THBS1, THBD, F2R, SERPINE2, F2, PROS1, AMBP, PROC, GP5, SERPINE1, SERPINB6, SPP1, IGFBP5, IGFBP3, S
Protein Size: 622 -
分子量
- 70 kDa
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基因ID
- 2147
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NCBI登录号
- NM_000506, NP_000497
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UniProt
- P00734
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途径
- Complement System, Peptide Hormone Metabolism, Regulation of G-Protein Coupled Receptor Protein Signaling
抗原
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