Amylin/DAP 抗体 (N-Term)
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- 抗原 See all Amylin/DAP (IAPP) 抗体
- Amylin/DAP (IAPP) (Islet Amyloid Polypeptide (IAPP))
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抗原表位
- N-Term
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适用
- 人, 兔, 犬, Cow, 马
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Amylin/DAP antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- MGILKLQVFL IVLSVALNHL KATPIESHQV EKRKCNTATC ATQRLANFLV
- 预测反应
- Cow: 82%, Dog: 86%, Horse: 93%, Human: 100%, Rabbit: 86%
- 产品特性
- This is a rabbit polyclonal antibody against IAPP. It was validated on Western Blot.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human IAPP
- Top Product
- Discover our top product IAPP Primary Antibody
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 89 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- Amylin/DAP (IAPP) (Islet Amyloid Polypeptide (IAPP))
- 别名
- IAPP (IAPP 产品)
- 别名
- DAP antibody, IAP antibody, LOC100230121 antibody, Amylin antibody, islet amyloid polypeptide antibody, IAPP antibody, Iapp antibody
- 背景
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Islet, or insulinoma, amyloid polypeptide is commonly found in pancreatic islets of patients suffering diabetes mellitus type II, or harboring an insulinoma. While the assosciation of amylin with the development of type II diabetes has been known for some time, a direct causative role for amylin has been harder to establish. Studies suggest that amylin, like the related beta-amyloid (Abeta) associated with Alzheimer's disease, can induce apoptotic cell-death in particular cultured cells, an effect that may be relevant to the development of type II diabetes.
Alias Symbols: AMYLIN, DAP, IAP
Protein Interaction Partner: COL25A1, RAMP2, RAMP1, PDX1, PCSK2, PCSK1,
Protein Size: 89 - 分子量
- 4 kDa
- 基因ID
- 3375
- NCBI登录号
- NM_000415, NP_000406
- UniProt
- P10997
- 途径
- Hormone Activity, Feeding Behaviour
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