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Amylin/DAP 抗体 (N-Term)

This anti-Amylin/DAP antibody is a 兔 多克隆 antibody detecting Amylin/DAP in WB. Suitable for 人, 兔, 犬, Cow 和 马.
产品编号 ABIN2776959
发货至: 中国

Quick Overview for Amylin/DAP 抗体 (N-Term) (ABIN2776959)

抗原

See all Amylin/DAP (IAPP) 抗体
Amylin/DAP (IAPP) (Islet Amyloid Polypeptide (IAPP))

适用

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人, 兔, 犬, Cow, 马

宿主

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克隆类型

  • 69
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多克隆

标记

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This Amylin/DAP antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    N-Term

    序列

    MGILKLQVFL IVLSVALNHL KATPIESHQV EKRKCNTATC ATQRLANFLV

    预测反应

    Cow: 82%, Dog: 86%, Horse: 93%, Human: 100%, Rabbit: 86%

    产品特性

    This is a rabbit polyclonal antibody against IAPP. It was validated on Western Blot.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the N terminal region of human IAPP
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 89 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    Amylin/DAP (IAPP) (Islet Amyloid Polypeptide (IAPP))

    别名

    IAPP

    背景

    Islet, or insulinoma, amyloid polypeptide is commonly found in pancreatic islets of patients suffering diabetes mellitus type II, or harboring an insulinoma. While the assosciation of amylin with the development of type II diabetes has been known for some time, a direct causative role for amylin has been harder to establish. Studies suggest that amylin, like the related beta-amyloid (Abeta) associated with Alzheimer's disease, can induce apoptotic cell-death in particular cultured cells, an effect that may be relevant to the development of type II diabetes.
    Alias Symbols: AMYLIN, DAP, IAP
    Protein Interaction Partner: COL25A1, RAMP2, RAMP1, PDX1, PCSK2, PCSK1,
    Protein Size: 89

    分子量

    4 kDa

    基因ID

    3375

    NCBI登录号

    NM_000415, NP_000406

    UniProt

    P10997

    途径

    Hormone Activity, Feeding Behaviour
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