PKLR 抗体 (N-Term)
Quick Overview for PKLR 抗体 (N-Term) (ABIN2776945)
抗原
See all PKLR 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- STSIIATIGP ASRSVERLKE MIKAGMNIAR LNFSHGSHEY HAESIANVRE
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预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 86%, Horse: 93%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%
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产品特性
- This is a rabbit polyclonal antibody against PKLR. It was validated on Western Blot and immunohistochemistry.
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纯化方法
- Protein A purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human PKLR
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 543 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- PKLR (Pyruvate Kinase, Liver and RBC (PKLR))
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别名
- PKLR
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背景
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PKLR is a pyruvate kinase that catalyzes the production of phohsphoenolpyruvate from pyruvate and ATP. Defects in this enzyme, due to gene mutations or genetic variations, are the common cause of chronic hereditary nonspherocytic hemolytic anemia (CNSHA or HNSHA).The protein encoded by this gene is a pyruvate kinase that catalyzes the production of phohsphoenolpyruvate from pyruvate and ATP. Defects in this enzyme, due to gene mutations or genetic variations, are the common cause of chronic hereditary nonspherocytic hemolytic anemia (CNSHA or HNSHA). Alternatively spliced transcript variants encoding distinct isoforms have been described.
Alias Symbols: PK1, PKL, RPK, PKR, PKRL
Protein Interaction Partner: UBC, WWOX, SUMO4, CLEC4G, PCNA, OTUD5, USPL1, USP3, MYOC, KIF23, ARHGEF6, PXN, PAK1,
Protein Size: 543 -
分子量
- 58 kDa
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基因ID
- 5313
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NCBI登录号
- NM_181871, NP_870986
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途径
- Ribonucleoside Biosynthetic Process
抗原
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