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Leptin 抗体 (N-Term)

This anti-Leptin antibody is a 兔 多克隆 antibody detecting Leptin in WB 和 IHC. Suitable for 人, 小鼠, 大鼠, Cow, 马, 犬, 山羊, 兔, 绵羊 和 豚鼠. This Primary Antibody has been cited in 1 publication.
产品编号 ABIN2776943
发货至: 中国

Quick Overview for Leptin 抗体 (N-Term) (ABIN2776943)

抗原

See all Leptin (LEP) 抗体
Leptin (LEP)

适用

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人, 小鼠, 大鼠, Cow, 马, 犬, 山羊, 兔, 绵羊, 豚鼠

宿主

  • 182
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克隆类型

  • 195
  • 46
多克隆

标记

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This Leptin antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

    • 40
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    N-Term

    序列

    MHWGTLCGFL WLWPYLFYVQ AVPIQKVQDD TKTLIKTIVT RINDISHTQS

    预测反应

    Cow: 86%, Dog: 86%, Goat: 91%, Guinea Pig: 79%, Horse: 79%, Human: 100%, Mouse: 100%, Rabbit: 79%, Rat: 100%, Sheep: 91%

    产品特性

    This is a rabbit polyclonal antibody against LEP. It was validated on Western Blot using a cell lysate as a positive control.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the N terminal region of human LEP
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 167 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Müller, Kowalewski, Reichler, Kollár, Balogh: "Different expression of leptin and IGF1 in the adult and prepubertal testis in dogs." in: Reproduction in domestic animals = Zuchthygiene, Vol. 52 Suppl 2, pp. 187-192, (2017) (PubMed).

  • 抗原

    Leptin (LEP)

    别名

    LEP

    背景

    LEP is a protein that is secreted by white adipocytes, and which plays a major role in the regulation of body weight. This protein, which acts through the leptin receptor, functions as part of a signaling pathway that can inhibit food intake and/or regula
    Alias Symbols: OB, OBS
    Protein Interaction Partner: Hk3, SIGLEC6, GHRL, LEPR, UCN, PRKAA2, CLU, CRP, A2M, STAT3,
    Protein Size: 167

    分子量

    19 kDa

    基因ID

    3952

    NCBI登录号

    NM_000230, NP_000221

    UniProt

    P41159

    途径

    JAK/STAT Signaling, AMPK Signaling, Hormone Transport, Peptide Hormone Metabolism, Hormone Activity, Negative Regulation of Hormone Secretion, Regulation of Carbohydrate Metabolic Process, Feeding Behaviour, Monocarboxylic Acid Catabolic Process
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