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ASL 抗体 (Middle Region)

Name: ASL 抗体 (Middle Region)
SKU: ABIN2776928
Availability: OutOfStock

This anti-ASL antibody is a 兔多克隆 antibody detecting ASL in WB. Suitable for 人, 小鼠, 大鼠, Cow, 斑马鱼, 豚鼠, 马, 兔, 犬, 山羊和 Saccharomyces cerevisiae. This Primary Antibody has been cited in 2+ publications.

WB Suggested Anti-ASL Antibody Titration: 5. (ASL 抗体 (Middle Region))

Lanes: Lane1: 10 ug COS-7 cell lysate Primary Antibody Dilution: 1:1000 Secondary Antibody: Anti-rabbit HRP Secondary Antibody Dilution: 1:2000 Gene Name: ASL Submitted by: Shawn Elms. (ASL 抗体 (Middle Region))

2 images

(2 references)

产品编号 ABIN2776928

发货至: 中国

Quick Overview for ASL 抗体 (Middle Region) (ABIN2776928)

抗原

See all ASL 抗体

ASL (Argininosuccinate Lyase (ASL))

适用

人, 小鼠, 大鼠, Cow, 斑马鱼, 豚鼠, 马, 兔, 犬, 山羊, Saccharomyces cerevisiae

宿主

兔

克隆类型

多克隆

标记

This ASL antibody is un-conjugated

应用范围

Western Blotting (WB)

Discover our top product ASL Primary Antibody

抗原表位
15

12

6

2

1

1

1

1

1

1

1

1

1

1
Middle Region

序列

LILYCTKEFS FVQLSDAYST GSSLMPQKKN PDSLELIRSK AGRVFGREDK

预测反应

Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 93%, Zebrafish: 93%

产品特性

This is a rabbit polyclonal antibody against ASL. It was validated on Western Blot using a cell lysate as a positive control.

纯化方法

Protein A purified

免疫原

The immunogen is a synthetic peptide directed towards the middle region of human ASL
anti-Argininosuccinate Lyase (ASL) antibody
ASL 适用: 人 WB, IF, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated

anti-Argininosuccinate Lyase (ASL) (AA 1-300) antibody
ASL 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Argininosuccinate Lyase (ASL) (AA 2-300) antibody
ASL 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Argininosuccinate Lyase (ASL) (AA 1-464) antibody
ASL 适用: 人 WB 宿主: 兔 Polyclonal unconjugated

anti-Argininosuccinate Lyase (ASL) antibody
ASL 适用: 人, 小鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Argininosuccinate Lyase (ASL) antibody
ASL 适用: 人, 小鼠, 大鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated

anti-Argininosuccinate Lyase (ASL) (AA 1-464) antibody
ASL 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated

anti-Argininosuccinate Lyase (ASL) (AA 260-309) antibody
ASL 适用: 人, 小鼠, 大鼠, Cow, 斑马鱼, 豚鼠, 马, 兔, Bat, 小鸡, Hamster, 猴, Pig WB 宿主: 兔 Polyclonal unconjugated

anti-Argininosuccinate Lyase (ASL) (AA 101-150) antibody
ASL 适用: 人, 小鼠, 大鼠, Cow, 斑马鱼, 豚鼠, 马, 兔, Bat, 小鸡, Hamster, 猴, Pig, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated

anti-Argininosuccinate Lyase (ASL) (Middle Region) antibody
ASL 适用: 人, 小鼠, 大鼠, 犬 WB 宿主: 兔 Polyclonal unconjugated

应用备注

Optimal working dilutions should be determined experimentally by the investigator.

说明

Antigen size: 444 AA

限制

仅限研究用
状态

Liquid

浓度

Lot specific

缓冲液

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

Avoid repeated freeze-thaw cycles.

储存条件

-20 °C

储存方法

For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Hu, Lausted, Yoo, Yan, Brightman, Chen, Wang, Bu, Hood: "Quantitative liver-specific protein fingerprint in blood: a signature for hepatotoxicity." in: Theranostics, Vol. 4, Issue 2, pp. 215-28, (2014) (PubMed).

Tanaka, Nagao, Mori, Tsutsumi: "A novel stop codon mutation (X465Y) in the argininosuccinate lyase gene in a patient with argininosuccinic aciduria." in: The Tohoku journal of experimental medicine, Vol. 198, Issue 2, pp. 119-24, (2003) (PubMed).
抗原

ASL (Argininosuccinate Lyase (ASL))

别名

ASL

背景

ASL is a member of the lyase 1 family. The protein forms a cytosolic homotetramer and primarily catalyzes the reversible hydrolytic cleavage of argininosuccinate into arginine and fumarate, an essential step in the liver in detoxifying ammonia via the urea cycle. Mutations in its gene result in the autosomal recessive disorder argininosuccinic aciduria, or argininosuccinic acid lyase deficiency.This gene encodes a member of the lyase 1 family. The encoded protein forms a cytosolic homotetramer and primarily catalyzes the reversible hydrolytic cleavage of argininosuccinate into arginine and fumarate, an essential step in the liver in detoxifying ammonia via the urea cycle. Mutations in this gene result in the autosomal recessive disorder argininosuccinic aciduria, or argininosuccinic acid lyase deficiency. A nontranscribed pseudogene is also located on the long arm of chromosome 22. Alternatively spliced transcript variants encoding different isoforms have been described.
Alias Symbols: ASAL
Protein Interaction Partner: WDYHV1, ASL, GINS4, NCDN, TUFM, PDHA1, NEDD8, HK1, GDI1, BAG3, OVGP1, HMOX1, FBP1, CSNK2A2, UBC, QARS,
Protein Size: 444

分子量

49 kDa

基因ID

435

NCBI登录号

NM_001024944, NP_001020115

UniProt

P04424

途径

Response to Growth Hormone Stimulus