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ASL 抗体 (N-Term)

This anti-ASL antibody is a 兔 多克隆 antibody detecting ASL in WB. Suitable for 人, 小鼠, 大鼠, Cow, 斑马鱼, 豚鼠, 马, 兔, 犬, 山羊 和 Saccharomyces cerevisiae. This Primary Antibody has been cited in 1 publication.
产品编号 ABIN2776927
发货至: 中国

Quick Overview for ASL 抗体 (N-Term) (ABIN2776927)

抗原

See all ASL 抗体
ASL (Argininosuccinate Lyase (ASL))

适用

  • 60
  • 14
  • 10
  • 5
  • 5
  • 5
  • 5
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  • 3
  • 3
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  • 2
人, 小鼠, 大鼠, Cow, 斑马鱼, 豚鼠, 马, 兔, 犬, 山羊, Saccharomyces cerevisiae

宿主

  • 55
  • 5

克隆类型

  • 57
  • 3
多克隆

标记

  • 31
  • 4
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This ASL antibody is un-conjugated

应用范围

  • 40
  • 13
  • 13
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  • 13
  • 12
  • 7
  • 6
  • 4
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
Western Blotting (WB)
  • 抗原表位

    • 15
    • 12
    • 6
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term

    序列

    GATAGKLHTG RSRNDQVVTD LRLWMRQTCS TLSGLLWELI RTMVDRAEAE

    预测反应

    Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 100%, Zebrafish: 100%

    产品特性

    This is a rabbit polyclonal antibody against ASL. It was validated on Western Blot using a cell lysate as a positive control.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the N terminal region of human ASL
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 464 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Trevisson, Salviati, Baldoin, Toldo, Casarin, Sacconi, Cesaro, Basso, Burlina: "Argininosuccinate lyase deficiency: mutational spectrum in Italian patients and identification of a novel ASL pseudogene." in: Human mutation, Vol. 28, Issue 7, pp. 694-702, (2007) (PubMed).

  • 抗原

    ASL (Argininosuccinate Lyase (ASL))

    别名

    ASL

    背景

    ASL is a member of the lyase 1 family. The protein forms a cytosolic homotetramer and primarily catalyzes the reversible hydrolytic cleavage of argininosuccinate into arginine and fumarate, an essential step in the liver in detoxifying ammonia via the urea cycle. Mutations in its gene result in the autosomal recessive disorder argininosuccinic aciduria, or argininosuccinic acid lyase deficiency.This gene encodes a member of the lyase 1 family. The encoded protein forms a cytosolic homotetramer and primarily catalyzes the reversible hydrolytic cleavage of argininosuccinate into arginine and fumarate, an essential step in the liver in detoxifying ammonia via the urea cycle. Mutations in this gene result in the autosomal recessive disorder argininosuccinic aciduria, or argininosuccinic acid lyase deficiency. A nontranscribed pseudogene is also located on the long arm of chromosome 22. Alternatively spliced transcript variants encoding different isoforms have been described.
    Alias Symbols: ASAL
    Protein Interaction Partner: WDYHV1, ASL, GINS4, NCDN, TUFM, PDHA1, NEDD8, HK1, GDI1, BAG3, OVGP1, HMOX1, FBP1, CSNK2A2, UBC, QARS,
    Protein Size: 464

    分子量

    52 kDa

    基因ID

    435

    NCBI登录号

    NM_000048, NP_000039

    UniProt

    P04424

    途径

    Response to Growth Hormone Stimulus
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