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Vitamin D Receptor 抗体 (N-Term)

This anti-Vitamin D Receptor antibody is a 兔多克隆 antibody detecting Vitamin D Receptor in WB. Suitable for 人.

WB Suggested Anti-VDR Antibody Titration: 0. (Vitamin D Receptor 抗体 (N-Term))

Host: Rabbit Target Name: VDR Sample Type: Human Fetal Liver Antibody Dilution: 1. (Vitamin D Receptor 抗体 (N-Term))

Host: Rabbit Target Name: VDR Sample Type: Human Adult Placenta Antibody Dilution: 1. (Vitamin D Receptor 抗体 (N-Term))

Host: Rabbit Target Name: VDR Sample Type: Human Fetal Muscle Antibody Dilution: 1. (Vitamin D Receptor 抗体 (N-Term))

Host: Rabbit Target Name: VDR Sample Type: Human Fetal Heart Antibody Dilution: 1. (Vitamin D Receptor 抗体 (N-Term))

5 images

产品编号 ABIN2776857

发货至: 中国

Quick Overview for Vitamin D Receptor 抗体 (N-Term) (ABIN2776857)

抗原

See all Vitamin D Receptor (VDR) 抗体

Vitamin D Receptor (VDR)

适用

96
60
44
2
1
1
1
1
1

人

宿主

兔

克隆类型

多克隆

标记

65
6
3
3
3
3
3
3
3
3
2
2
2
2
2
2
2
2
2
2
2
2
1

This Vitamin D Receptor antibody is un-conjugated

应用范围

94
34
26
26
22
13
13
11
11
10
6
2
2
1
1

Western Blotting (WB)

Discover our top product VDR Primary Antibody

抗原表位
15

15

13

13

7

4

3

3

3

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
N-Term

序列

EAMAASTSLP DPGDFDRNVP RICGVCGDRA TGFHFNAMTC EGCKGFFRRS

预测反应

Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

产品特性

This is a rabbit polyclonal antibody against VDR. It was validated on Western Blot using a cell lysate as a positive control.

纯化方法

Affinity Purified

免疫原

The immunogen is a synthetic peptide directed towards the N terminal region of human VDR
anti-Vitamin D Receptor (VDR) (AA 65-180) antibody
VDR 适用: 人, 小鼠, 大鼠 WB, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Vitamin D Receptor (VDR) (AA 1-427) antibody
VDR 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated

anti-Vitamin D Receptor (VDR) (AA 1-300) antibody
VDR 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Vitamin D Receptor (VDR) (AA 377-402), (C-Term) antibody
VDR 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-Vitamin D Receptor (VDR) (pSer208) antibody
VDR 适用: 人 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Vitamin D Receptor (VDR) (AA 266-422) antibody
VDR 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Vitamin D Receptor (VDR) antibody
VDR 适用: 人 WB, ELISA, IHC 宿主: 兔 Monoclonal 3C7 unconjugated Recombinant Antibody

anti-Vitamin D Receptor (VDR) (AA 1-428) antibody
VDR 适用: 人 ELISA, IHC, IHC (p) 宿主: 小鼠 Monoclonal 2F4 unconjugated

anti-Vitamin D Receptor (VDR) (AA 1-427) antibody
VDR 适用: 人 ELISA, IHC (p) 宿主: 小鼠 Monoclonal 2F4 unconjugated

anti-Vitamin D Receptor (VDR) (AA 181-230) antibody
VDR 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated

应用备注

Optimal working dilutions should be determined experimentally by the investigator.

说明

Antigen size: 427 AA

限制

仅限研究用
状态

Liquid

浓度

Lot specific

缓冲液

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

Avoid repeated freeze-thaw cycles.

储存条件

-20 °C

储存方法

For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
抗原

Vitamin D Receptor (VDR)

别名

VDR

物质类

Chemical

背景

The nuclear hormone receptor for vitamin D3 also functions as a receptor for the secondary bile acid lithocholic acid. The receptor belongs to the family of trans-acting transcriptional regulatory factors and shows sequence similarity to the steroid and thyroid hormone receptors. Downstream targets of this nuclear hormone receptor are principally involved in mineral metabolism though the receptor regulates a variety of other metabolic pathways, such as those involved in the immune response and cancer. Mutations in this gene are associated with type II vitamin D-resistant rickets. A single nucleotide polymorphism in the initiation codon results in an alternate translation start site three codons downstream. Alternative splicing results in multiple transcript variants encoding the same protein.This gene encodes the nuclear hormone receptor for vitamin D3. This receptor also functions as a receptor for the secondary bile acid lithocholic acid. The receptor belongs to the family of trans-acting transcriptional regulatory factors and shows sequence similarity to the steroid and thyroid hormone receptors. Downstream targets of this nuclear hormone receptor are principally involved in mineral metabolism though the receptor regulates a variety of other metabolic pathways, such as those involved in the immune response and cancer. Mutations in this gene are associated with type II vitamin D-resistant rickets. A single nucleotide polymorphism in the initiation codon results in an alternate translation start site three codons downstream. Alternative splicing results in multiple transcript variants encoding the same protein.
Alias Symbols: NR1I1
Protein Interaction Partner: MED12, MED24, BAZ1B, SMARCA4, RXRA, MED1, NCOA2, NSD1, NCOA1, SRPK1, PTPN3, Hr, NKD2, MMRN2, CDCA7L, CXXC5, UBC, RXRB, PRKCSH, PRCP, CFH, CCND3, MYC, MXD1, BRCA1, PSMC5, NCOR1, SRC, NCOA6, PPP1CC, CDK11B, NR1H2, RXRG, CASC4, GABARAPL1, GABARAPL2, CLASRP,
Protein Size: 427

分子量

48 kDa

基因ID

7421

NCBI登录号

NM_000376, NP_000367

UniProt

P11473

途径

Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway

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