Desmin 抗体 (N-Term)
Quick Overview for Desmin 抗体 (N-Term) (ABIN2776842)
抗原
See all Desmin (DES) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- PLSSPVFPRA GFGSKGSSSS VTSRVYQVSR TSGGAGGLGS LRASRLGTTR
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预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%
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产品特性
- This is a rabbit polyclonal antibody against DES. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Protein A purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human DES
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 470 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Desmin (DES)
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别名
- DES
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背景
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DES is a muscle-specific class III intermediate filament. Homopolymers of this protein form a stable intracytoplasmic filamentous network connecting myofibrils to each other and to the plasma membrane. Mutations in its gene are associated with desmin-related myopathy, a familial cardiac and skeletal myopathy (CSM), and with distal myopathies.This gene encodes a muscle-specific class III intermediate filament. Homopolymers of this protein form a stable intracytoplasmic filamentous network connecting myofibrils to each other and to the plasma membrane. Mutations in this gene are associated with desmin-related myopathy, a familial cardiac and skeletal myopathy (CSM), and with distal myopathies.
Alias Symbols: CMD1I, CSM1, CSM2, FLJ12025, FLJ39719, FLJ41013, FLJ41793
Protein Interaction Partner: PPP1R18, UBE2I, EHHADH, TRIM63, TRIM55, UBC, YWHAQ, MAPKAPK2, CAPN1, MLH1, AURKB, HADHB, MYL6, JUP, HSP90AA5P, HNRNPUL1, CCT7, SNRNP70, RPL29, RPL17, UBD, CRYAB, SHBG, SP1, ITSN1, NEB, PLEKHA5, SYNC, TRIM7, SYNM, ROCK1, PKD1, SPTAN1, S100B, S100A1, DSP,
Protein Size: 470 -
分子量
- 52 kDa
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基因ID
- 1674
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NCBI登录号
- NM_001927, NP_001918
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UniProt
- P17661
抗原
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