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Desmin 抗体 (N-Term)

This 兔 多克隆 anti-Desmin antibody specifically detects Desmin in WB. The antibody is reactive with 人, 大鼠, 小鼠, 犬, Cow, 兔, 马 和 豚鼠 samples.
产品编号 ABIN2776842
发货至: 中国
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Quick Overview for Desmin 抗体 (N-Term) (ABIN2776842)

抗原

See all Desmin (DES) 抗体
Desmin (DES)

适用

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人, 大鼠, 小鼠, 犬, Cow, 兔, 马, 豚鼠

宿主

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克隆类型

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多克隆

标记

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This Desmin antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    N-Term

    序列

    PLSSPVFPRA GFGSKGSSSS VTSRVYQVSR TSGGAGGLGS LRASRLGTTR

    预测反应

    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

    产品特性

    This is a rabbit polyclonal antibody against DES. It was validated on Western Blot using a cell lysate as a positive control.

    纯化方法

    Protein A purified

    免疫原

    The immunogen is a synthetic peptide directed towards the N terminal region of human DES
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 470 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    Desmin (DES)

    别名

    DES

    背景

    DES is a muscle-specific class III intermediate filament. Homopolymers of this protein form a stable intracytoplasmic filamentous network connecting myofibrils to each other and to the plasma membrane. Mutations in its gene are associated with desmin-related myopathy, a familial cardiac and skeletal myopathy (CSM), and with distal myopathies.This gene encodes a muscle-specific class III intermediate filament. Homopolymers of this protein form a stable intracytoplasmic filamentous network connecting myofibrils to each other and to the plasma membrane. Mutations in this gene are associated with desmin-related myopathy, a familial cardiac and skeletal myopathy (CSM), and with distal myopathies.
    Alias Symbols: CMD1I, CSM1, CSM2, FLJ12025, FLJ39719, FLJ41013, FLJ41793
    Protein Interaction Partner: PPP1R18, UBE2I, EHHADH, TRIM63, TRIM55, UBC, YWHAQ, MAPKAPK2, CAPN1, MLH1, AURKB, HADHB, MYL6, JUP, HSP90AA5P, HNRNPUL1, CCT7, SNRNP70, RPL29, RPL17, UBD, CRYAB, SHBG, SP1, ITSN1, NEB, PLEKHA5, SYNC, TRIM7, SYNM, ROCK1, PKD1, SPTAN1, S100B, S100A1, DSP,
    Protein Size: 470

    分子量

    52 kDa

    基因ID

    1674

    NCBI登录号

    NM_001927, NP_001918

    UniProt

    P17661
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