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Renin 抗体 (C-Term)

Name: Renin 抗体 (C-Term)
SKU: ABIN2776795
Availability: OutOfStock

This anti-Renin antibody is a 兔多克隆 antibody detecting Renin in WB. Suitable for 人, 大鼠, 小鼠, 犬, 兔, 绵羊, Cow, 豚鼠和马. This Primary Antibody has been cited in 1 publication.

WB Suggested Anti-REN Antibody Titration: 2. (Renin 抗体 (C-Term))

Host: Mouse Target Name: REN1 Sample Tissue: Mouse Heart Antibody Dilution: 1ug/ml (Renin 抗体 (C-Term))

2 images

(1 reference)

产品编号 ABIN2776795

发货至: 中国

Quick Overview for Renin 抗体 (C-Term) (ABIN2776795)

抗原

See all Renin (REN) 抗体

Renin (REN)

适用

人, 大鼠, 小鼠, 犬, 兔, 绵羊, Cow, 豚鼠, 马

宿主

兔

克隆类型

多克隆

标记

This Renin antibody is un-conjugated

应用范围

Western Blotting (WB)

Discover our top product REN Primary Antibody

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C-Term

序列

YSSKKLCTLA IHAMDIPPPT GPTWALGATF IRKFYTEFDR RNNRIGFALA

预测反应

Cow: 100%, Dog: 93%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%, Sheep: 100%

产品特性

This is a rabbit polyclonal antibody against REN. It was validated on Western Blot using a cell lysate as a positive control.

纯化方法

Protein A purified

免疫原

The immunogen is a synthetic peptide directed towards the C terminal region of human REN
anti-Renin (REN) (AA 67-153) antibody
REN 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Renin (REN) (AA 24-406) antibody
REN 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2H2 unconjugated

anti-Renin (REN) (Internal Region) antibody
REN 适用: 人, 小鼠 WB, IHC, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated

anti-Renin (REN) (AA 331-406) antibody
REN 适用: 大鼠, 小鼠, 犬 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Renin (REN) (AA 67-153) antibody
REN 适用: 人 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal D2 unconjugated

anti-Renin (REN) (AA 275-389) antibody
REN 适用: 大鼠 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal 3# unconjugated

anti-Renin (REN) (AA 65-264) antibody
REN 适用: 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated

anti-Renin (REN) (AA 229-398) antibody
REN 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated

anti-Renin (REN) antibody
REN 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated

anti-Renin (REN) (AA 24-406) antibody
REN 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 3B5 unconjugated

应用备注

Optimal working dilutions should be determined experimentally by the investigator.

说明

Antigen size: 406 AA

限制

仅限研究用
状态

Liquid

浓度

Lot specific

缓冲液

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

Avoid repeated freeze-thaw cycles.

储存条件

-20 °C

储存方法

For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Kumai, Bernier, Perry: "Angiotensin-II promotes Na+ uptake in larval zebrafish, Danio rerio, in acidic and ion-poor water." in: The Journal of endocrinology, Vol. 220, Issue 3, pp. 195-205, (2014) (PubMed).
抗原

Renin (REN)

别名

REN

背景

Renin catalyzes the first step in the activation pathway of angiotensinogen--a cascade that can result in aldosterone release,vasoconstriction, and increase in blood pressure. Renin, an aspartyl protease, cleaves angiotensinogen to form angiotensin I, which is converted to angiotensin II by angiotensin I converting enzyme, an important regulator of blood pressure and electrolyte balance. Mutations in this gene have been shown to cause familial hyperproreninemia.Renin catalyzes the first step in the activation pathway of angiotensinogen--a cascade that can result in aldosterone release,vasoconstriction, and increase in blood pressure. Renin, an aspartyl protease, cleaves angiotensinogen to form angiotensin I, which is converted to angiotensin II by angiotensin I converting enzyme, an important regulator of blood pressure and electrolyte balance. Transcript variants that encode different protein isoforms and that arise from alternative splicing and the use of alternative promoters have been described, but their full-length nature has not been determined. Mutations in this gene have been shown to cause familial hyperproreninemia.
Alias Symbols: FLJ10761, HNFJ2
Protein Interaction Partner: AGT, ATP6AP2, KCTD15, PCSK5, RENBP, PCSK1, M6PR, CTSB,
Protein Size: 406

分子量

45 kDa

基因ID

5972

NCBI登录号

NM_000537, NP_000528

UniProt

P00797

途径

ACE Inhibitor Pathway, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones, Feeding Behaviour