Tropomyosin 抗体 (N-Term)
Quick Overview for Tropomyosin 抗体 (N-Term) (ABIN2776783)
抗原
See all Tropomyosin (TPM1) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- DRAEQAEADK KAAEDRSKQL EDELVSLQKK LKGTEDELDK YSEALKDAQE
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预测反应
- Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 93%, Zebrafish: 100%
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产品特性
- This is a rabbit polyclonal antibody against TPM1. It was validated on Western Blot and immunohistochemistry.
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纯化方法
- Protein A purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human TPM1
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anti-Tropomyosin 1 (Alpha) (TPM1) (AA 1-245) antibody
TPM1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Tropomyosin 1 (Alpha) (TPM1) antibodyTPM1 适用: 人 WB, IHC, IF, IP 宿主: 兔 Monoclonal unconjugated
anti-Tropomyosin 1 (Alpha) (TPM1) antibodyTPM1 适用: 大鼠, 小鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Tropomyosin 1 (Alpha) (TPM1) antibodyTPM1 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Tropomyosin 1 (Alpha) (TPM1) (N-Term) antibodyTPM1 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Tropomyosin 1 (Alpha) (TPM1) antibodyTPM1 适用: 人, 大鼠, 小鼠, 斑马鱼, 犬 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Tropomyosin 1 (Alpha) (TPM1) (AA 101-150) antibodyTPM1 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Tropomyosin 1 (Alpha) (TPM1) (N-Term) antibodyTPM1 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Tropomyosin 1 (Alpha) (TPM1) (N-Term) antibodyTPM1 适用: 人, 大鼠, 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Tropomyosin 1 (Alpha) (TPM1) antibodyTPM1 适用: 人, 大鼠, 小鼠 WB, IF, IC 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 284 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Tropomyosin (TPM1) (Tropomyosin 1 (Alpha) (TPM1))
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别名
- TPM1
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背景
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TPM1 is a member of the tropomyosin family of highly conserved, widely distributed actin-binding proteins involved in the contractile system of striated and smooth muscles and the cytoskeleton of non-muscle cells. Tropomyosin is composed of two alpha-helical chains arranged as a coiled-coil. It is polymerized end to end along the two grooves of actin filaments and provides stability to the filaments. The protein is one type of alpha helical chain that forms the predominant tropomyosin of striated muscle, where it also functions in association with the troponin complex to regulate the calcium-dependent interaction of actin and myosin during muscle contraction.This gene is a member of the tropomyosin family of highly conserved, widely distributed actin-binding proteins involved in the contractile system of striated and smooth muscles and the cytoskeleton of non-muscle cells. Tropomyosin is composed of two alpha-helical chains arranged as a coiled-coil. It is polymerized end to end along the two grooves of actin filaments and provides stability to the filaments. The encoded protein is one type of alpha helical chain that forms the predominant tropomyosin of striated muscle, where it also functions in association with the troponin complex to regulate the calcium-dependent interaction of actin and myosin during muscle contraction. In smooth muscle and non-muscle cells, alternatively spliced transcript variants encoding a range of isoforms have been described. Mutations in this gene are associated with type 3 familial hypertrophic cardiomyopathy.
Alias Symbols: CMH3, TMSA, TPM1-alpha, CMD1Y, C15orf13, HTM-alpha
Protein Interaction Partner: GOLGA2, CAGE1, C1orf216, SYCE1, KXD1, TFPT, MAD1L1, TPM4, TP53, TNNT1, UBC, MDM2, ETFA, FOXK1, KIAA1598, PPP6R3, APPL2, CDC37, MGEA5, STUB1, ABI2, DNAJC7, HSP90B1, PARK2, LRCH3, PAN2, TGFBR1, SPTBN1, ATF2, MDC1, BRCA1, PPP4R2, SRXN1, NUDCD2, RBM15, THOC2,
Protein Size: 284 -
分子量
- 31 kDa
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基因ID
- 7168
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NCBI登录号
- NM_000366, NP_000357
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UniProt
- P09493
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途径
- Regulation of Actin Filament Polymerization
抗原
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