HSD11B2 抗体 (N-Term)
Quick Overview for HSD11B2 抗体 (N-Term) (ABIN2776772)
抗原
See all HSD11B2 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- N-Term
-
序列
- ERWPWPSGGA WLLVAARALL QLLRSDLRLG RPLLAALALL AALDWLCQRL
-
预测反应
- Cow: 100%, Guinea Pig: 100%, Horse: 92%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%
-
产品特性
- This is a rabbit polyclonal antibody against HSD11B2. It was validated on Western Blot using a cell lysate as a positive control.
-
纯化方法
- Affinity Purified
-
免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human HSD11B2
-
-
-
-
应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
-
说明
-
Antigen size: 44 AA
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- Lot specific
-
缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- Avoid repeated freeze-thaw cycles.
-
储存条件
- -20 °C
-
储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
-
-
- HSD11B2 (Hydroxysteroid (11-Beta) Dehydrogenase 2 (HSD11B2))
-
别名
- HSD11B2
-
背景
-
HSD11B2 catalyzes the conversion of cortisol to the inactive metabolite cortisone. It modulates intracellular glucocorticoid levels, thus protecting the nonselective mineralocorticoid receptor from occupation by glucocorticoids.
Alias Symbols: AME, AME1, HSD11K, HSD2, SDR9C3
Protein Interaction Partner: KAT2B, HDAC1, KAT2A, CTBP1,
Protein Size: 44 -
分子量
- 45 kDa
-
基因ID
- 3291
-
NCBI登录号
- NM_000196, NP_000187
-
UniProt
- P80365
-
途径
- Steroid Hormone Biosynthesis, Regulation of Systemic Arterial Blood Pressure by Hormones
抗原
-