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CDC25B 抗体 (N-Term)

This anti-CDC25B antibody is a 兔 多克隆 antibody detecting CDC25B in WB 和 IHC. Suitable for 人, 小鼠, 大鼠, 犬, 豚鼠, 马, Cow 和 兔.
产品编号 ABIN2776752
发货至: 中国

Quick Overview for CDC25B 抗体 (N-Term) (ABIN2776752)

抗原

See all CDC25B 抗体
CDC25B (Cell Division Cycle 25 Homolog B (S. Pombe) (CDC25B))

适用

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人, 小鼠, 大鼠, 犬, 豚鼠, 马, Cow, 兔

宿主

  • 200
  • 2

克隆类型

  • 190
  • 12
多克隆

标记

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This CDC25B antibody is un-conjugated

应用范围

  • 170
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Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

    • 28
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    • 15
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    N-Term

    序列

    TQTMHDLAGL GSETPKSQVG TLLFRSRSRL THLSLSRRAS ESSLSSESSE

    预测反应

    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 86%, Rabbit: 93%, Rat: 100%

    产品特性

    This is a rabbit polyclonal antibody against CDC25B. It was validated on Western Blot and immunohistochemistry.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the N terminal region of human CDC25B
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 580 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    CDC25B (Cell Division Cycle 25 Homolog B (S. Pombe) (CDC25B))

    别名

    CDC25B

    背景

    CDC25B is a member of the CDC25 family of phosphatases. CDC25B activates the cyclin dependent kinase CDC2 by removing two phosphate groups and it is required for entry into mitosis. CDC25B shuttles between the nucleus and the cytoplasm due to nuclear localization and nuclear export signals. The protein is nuclear in the M and G1 phases of the cell cycle and moves to the cytoplasm during S and G2. CDC25B has oncogenic properties, although its role in tumor formation has not been determined.CDC25B is a member of the CDC25 family of phosphatases. CDC25B activates the cyclin dependent kinase CDC2 by removing two phosphate groups and it is required for entry into mitosis. CDC25B shuttles between the nucleus and the cytoplasm due to nuclear localization and nuclear export signals. The protein is nuclear in the M and G1 phases of the cell cycle and moves to the cytoplasm during S and G2. CDC25B has oncogenic properties, although its role in tumor formation has not been determined. Multiple transcript variants for this gene exist.
    Protein Interaction Partner: BTRC, UBC, FBXW11, MAPK9, CDK5, CDK1, YWHAQ, MAPKAPK2, UBD, BRSK2, CDC14A, CDK2, Cdc25b, FOXM1, BRSK1, FHL3, KAT2B, MELK, YWHAE, CHEK1, AURKA, SFN, YWHAB, YWHAZ, MAPK14, CREBBP, AR, ESR1, CSNK2B, CSNK2A1, YWHAH, PGR, PHB2, KRT85, KRT35, KRT31,
    Protein Size: 580

    分子量

    65 kDa

    基因ID

    994

    NCBI登录号

    NM_021873, NP_068659

    UniProt

    P30305

    途径

    Cell Division Cycle, M Phase, Autophagy
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