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FZD7 抗体 (C-Term)

Cited in 5+ publications. The 兔多克隆 anti-FZD7 antibody (ABIN184104) specifically detects FZD7 in WB 和 IHC. The antibody is reactive with 人, 小鼠, 大鼠, 犬, Cow, 兔, Pig, 豚鼠和 Saccharomyces cerevisiae samples.

Rabbit Anti-FZD7 Antibody Paraffin Embedded Tissue: Human Kidney Cellular Data: Epithelial cells of renal tubule Antibody Concentration: 4. (FZD7 抗体 (C-Term))

IHC

Host: Rabbit Target Name: FZD7 Sample Tissue: Human A549 Whole Cell Antibody Dilution: 1ug/ml (FZD7 抗体 (C-Term))

Host: Rabbit Target Name: FZD7 Sample Tissue: Human Ovary Tumor Antibody Dilution: 1. (FZD7 抗体 (C-Term))

4 images

(5 references)

产品编号 ABIN184104

发货至: 中国

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Quick Overview for FZD7 抗体 (C-Term) (ABIN184104)

抗原

See all FZD7 抗体

FZD7 (Frizzled Family Receptor 7 (FZD7))

适用

人, 小鼠, 大鼠, 犬, Cow, 兔, Pig, 豚鼠, Saccharomyces cerevisiae

宿主

兔

克隆类型

多克隆

标记

This FZD7 antibody is un-conjugated

应用范围

Western Blotting (WB), Immunohistochemistry (IHC)

Discover our top product FZD7 Primary Antibody

抗原表位
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C-Term

序列

PDFTVFMIKY LMTMIVGITT GFWIWSGKTL QSWRRFYHRL SHSSKGETAV

预测反应

Cow: 100%, Dog: 100%, Guinea Pig: 93%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Yeast: 82%

产品特性

This is a rabbit polyclonal antibody against FZD7. It was validated on Western Blot and immunohistochemistry.

纯化方法

Affinity Purified

免疫原

The immunogen is a synthetic peptide directed towards the C terminal region of human FZD7
anti-Frizzled Family Receptor 7 (FZD7) (AA 501-574) antibody
FZD7 适用: 人, 小鼠, 大鼠 WB, ELISA, FACS, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Frizzled Family Receptor 7 (FZD7) (AA 155-253) antibody
FZD7 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 4D9 unconjugated

anti-Frizzled Family Receptor 7 (FZD7) (C-Term) antibody
FZD7 适用: 人, 小鼠, 大鼠, 犬, Cow, 兔, Pig, 豚鼠, Saccharomyces cerevisiae WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-Frizzled Family Receptor 7 (FZD7) (N-Term) antibody
FZD7 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated

anti-Frizzled Family Receptor 7 (FZD7) (AA 161-239) antibody
FZD7 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated

anti-Frizzled Family Receptor 7 (FZD7) (C-Term) antibody
Verified FZD7 适用: 人 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated

anti-Frizzled Family Receptor 7 (FZD7) (C-Term) antibody
FZD7 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Frizzled Family Receptor 7 (FZD7) (C-Term) antibody
FZD7 适用: 人, 小鼠, 大鼠, 犬, Cow, 兔, Bat, 猴, Pig WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-Frizzled Family Receptor 7 (FZD7) (N-Term) antibody
FZD7 适用: 人, 小鼠 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated

anti-Frizzled Family Receptor 7 (FZD7) (N-Term) antibody
FZD7 适用: 人, 小鼠, 大鼠, 犬, Cow, 兔, Bat, 猴, Pig, Hamster IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated

应用备注

Optimal working dilutions should be determined experimentally by the investigator.

说明

Antigen size: 574 AA

限制

仅限研究用
状态

Liquid

浓度

Lot specific

缓冲液

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

Avoid repeated freeze-thaw cycles.

储存条件

-20 °C

储存方法

For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
McIver, Stanger, Santarelli, Roman, Nixon, McLaughlin: "A unique combination of male germ cell miRNAs coordinates gonocyte differentiation." in: PLoS ONE, Vol. 7, Issue 4, pp. e35553, (2012) (PubMed).

Schmuck, Warneke, Behrens, Simon, Weichert, Röcken: "Genotypic and phenotypic characterization of side population of gastric cancer cell lines." in: The American journal of pathology, Vol. 178, Issue 4, pp. 1792-804, (2011) (PubMed).

Gökmen-Polar, Toroni, Hocevar, Badve, Zhao, Shen, Bruckheimer, Kinch, Miller: "Dual targeting of EphA2 and ER restores tamoxifen sensitivity in ER/EphA2-positive breast cancer." in: Breast cancer research and treatment, Vol. 127, Issue 2, pp. 375-84, (2011) (PubMed).

Ohba, Lanigan, Roessler: "Leptin receptor JAK2/STAT3 signaling modulates expression of Frizzled receptors in articular chondrocytes." in: Osteoarthritis and cartilage / OARS, Osteoarthritis Research Society, Vol. 18, Issue 12, pp. 1620-9, (2010) (PubMed).

Ueno, Hiura, Suehiro, Hazama, Hirata, Oka, Imai, Dahiya, Hinoda: "Frizzled-7 as a potential therapeutic target in colorectal cancer." in: Neoplasia (New York, N.Y.), Vol. 10, Issue 7, pp. 697-705, (2008) (PubMed).
抗原

FZD7 (Frizzled Family Receptor 7 (FZD7))

别名

FZD7

背景

FZD7 is 7-transmembrane domain protein that is receptor for Wnt signaling proteins. The FZD7 protein contains an N-terminal signal sequence, 10 cysteine residues typical of the cysteine-rich extracellular domain of Fz family members, 7 putative transmembrane domains, and an intracellular C-terminal tail with a PDZ domain-binding motif.Members of the 'frizzled' gene family encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The FZD7 protein contains an N-terminal signal sequence, 10 cysteine residues typical of the cysteine-rich extracellular domain of Fz family members, 7 putative transmembrane domains, and an intracellular C-terminal tail with a PDZ domain-binding motif. FZD7 gene expression may downregulate APC function and enhance beta-catenin-mediated signals in poorly differentiated human esophageal carcinomas.
Alias Symbols: FzE3
Protein Interaction Partner: UBC, UBQLN4, MAGI3, UBQLN1, DLG2, DLG4, DLG1,
Protein Size: 574

分子量

63 kDa

基因ID

8324

NCBI登录号

NM_003507, NP_003498

UniProt

O75084

途径

WNT signaling, Stem Cell Maintenance