DCP2 抗体 (C-Term)
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- 抗原 See all DCP2 抗体
- DCP2 (DCP2 Decapping Enzyme Homolog (DCP2))
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抗原表位
- C-Term
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适用
- 人, 小鼠, 大鼠, 豚鼠, Pig, 犬, 马, Cow
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This DCP2 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- VEKLSRTKFR HSQQLFPDGS PGDQWVKHRQ PLQQKPYNNH SEMSDLLKGK
- 预测反应
- Cow: 86%, Dog: 93%, Guinea Pig: 86%, Horse: 100%, Human: 100%, Mouse: 79%, Pig: 100%, Rat: 86%
- 产品特性
- This is a rabbit polyclonal antibody against DCP2. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the C terminal region of human DCP2
- Top Product
- Discover our top product DCP2 Primary Antibody
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 420 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- DCP2 (DCP2 Decapping Enzyme Homolog (DCP2))
- 别名
- DCP2 (DCP2 产品)
- 别名
- DDBDRAFT_0185453 antibody, DDBDRAFT_0252811 antibody, DDB_0185453 antibody, DDB_0252811 antibody, 2410015D23Rik antibody, 5730537H01Rik antibody, AL118268 antibody, NUDT20 antibody, RGD1562909 antibody, mRNA-decapping enzyme 2 antibody, hypothetical protein antibody, decapping mRNA 2 antibody, CpipJ_CPIJ019463 antibody, PTRG_05936 antibody, dcp2 antibody, MCYG_05106 antibody, MGYG_07617 antibody, PGTG_03310 antibody, Tsp_04018 antibody, DCP2 antibody, Dcp2 antibody
- 背景
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DCP2 is necessary for the degradation of mRNAs, both in normal mRNA turnover and in nonsense-mediated mRNA decay. DCP2 removes the 7-methyl guanine cap structure from mRNA molecules, yielding a 5'-phosphorylated mRNA fragment and 7m-GDP. It has higher activity towards mRNAs that lack a poly(A) tail, but has no activity towards a cap structure lacking a RNA moiety.DCP2 is a key component of an mRNA-decapping complex required for removal of the 5-prime cap from mRNA prior to its degradation from the 5-prime end (Fenger-Gron et al., 2005 [PubMed 16364915]).[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-539 AY135173.1 1-539 540-1992 AK090564.1 481-1933 1993-8947 AC008536.7 154323-161277
Alias Symbols: FLJ33245, NUDT20
Protein Interaction Partner: FAM96B, DCP1A, UBC, EDC4, DCP1B, SFXN2, ANGEL2, ARMCX5, DARS2, ELP3, QPCTL, GTPBP2, TRMT2A, FBXO3, INTS7, POLD3, GFPT2, AP1M1, SQSTM1, IKBKAP, TRRAP, TARS, ABCE1, PHKB, PGM3, PFKM, IDE, GLUD1, GGT7, GGCX, GFPT1, GARS, FANCD2, EIF5A, SLC25A10, CAPN2, NAGK,
Protein Size: 420 - 分子量
- 48 kDa
- 基因ID
- 167227
- NCBI登录号
- NM_152624, NP_689837
- UniProt
- Q8IU60
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