DCP2 抗体 (C-Term)
Quick Overview for DCP2 抗体 (C-Term) (ABIN2776652)
抗原
See all DCP2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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序列
- VEKLSRTKFR HSQQLFPDGS PGDQWVKHRQ PLQQKPYNNH SEMSDLLKGK
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预测反应
- Cow: 86%, Dog: 93%, Guinea Pig: 86%, Horse: 100%, Human: 100%, Mouse: 79%, Pig: 100%, Rat: 86%
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产品特性
- This is a rabbit polyclonal antibody against DCP2. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the C terminal region of human DCP2
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anti-DCP2 Decapping Enzyme Homolog (DCP2) (AA 1-240) antibody
DCP2 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-DCP2 Decapping Enzyme Homolog (DCP2) (AA 1-385) antibodyDCP2 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-DCP2 Decapping Enzyme Homolog (DCP2) (C-Term) antibodyDCP2 适用: 人 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-DCP2 Decapping Enzyme Homolog (DCP2) (AA 1-385) antibodyDCP2 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-DCP2 Decapping Enzyme Homolog (DCP2) (AA 144-173) antibodyDCP2 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB23240 unconjugated
anti-DCP2 Decapping Enzyme Homolog (DCP2) (AA 151-181), (Middle Region) antibodyDCP2 适用: 人 WB, FACS, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
anti-DCP2 Decapping Enzyme Homolog (DCP2) (AA 265-314) antibodyDCP2 适用: 人, 小鼠, 大鼠, 豚鼠, 马, Pig, Bat WB 宿主: 兔 Polyclonal unconjugated
anti-DCP2 Decapping Enzyme Homolog (DCP2) (AA 324-373) antibodyDCP2 适用: 人, 豚鼠, 犬, 兔, Bat, 猴 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 420 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- DCP2 (DCP2 Decapping Enzyme Homolog (DCP2))
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别名
- DCP2
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背景
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DCP2 is necessary for the degradation of mRNAs, both in normal mRNA turnover and in nonsense-mediated mRNA decay. DCP2 removes the 7-methyl guanine cap structure from mRNA molecules, yielding a 5'-phosphorylated mRNA fragment and 7m-GDP. It has higher activity towards mRNAs that lack a poly(A) tail, but has no activity towards a cap structure lacking a RNA moiety.DCP2 is a key component of an mRNA-decapping complex required for removal of the 5-prime cap from mRNA prior to its degradation from the 5-prime end (Fenger-Gron et al., 2005 [PubMed 16364915]).[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-539 AY135173.1 1-539 540-1992 AK090564.1 481-1933 1993-8947 AC008536.7 154323-161277
Alias Symbols: FLJ33245, NUDT20
Protein Interaction Partner: FAM96B, DCP1A, UBC, EDC4, DCP1B, SFXN2, ANGEL2, ARMCX5, DARS2, ELP3, QPCTL, GTPBP2, TRMT2A, FBXO3, INTS7, POLD3, GFPT2, AP1M1, SQSTM1, IKBKAP, TRRAP, TARS, ABCE1, PHKB, PGM3, PFKM, IDE, GLUD1, GGT7, GGCX, GFPT1, GARS, FANCD2, EIF5A, SLC25A10, CAPN2, NAGK,
Protein Size: 420 -
分子量
- 48 kDa
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基因ID
- 167227
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NCBI登录号
- NM_152624, NP_689837
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UniProt
- Q8IU60
抗原
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