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A1CF 抗体 (N-Term)

A1CF 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2776627
发货至: 中国
  • 抗原 See all A1CF 抗体
    A1CF (APOBEC1 Complementation Factor (A1CF))
    抗原表位
    • 9
    • 8
    • 7
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    N-Term
    适用
    • 27
    • 7
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    宿主
    • 26
    • 2
    克隆类型
    • 28
    多克隆
    标记
    • 18
    • 2
    • 2
    • 2
    • 2
    • 2
    This A1CF antibody is un-conjugated
    应用范围
    • 25
    • 16
    • 14
    • 13
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    序列
    EAVCLGTCPE PEASMSTAIP GLKKGNNALQ SIILQTLLEK ENGQRKYGGP
    预测反应
    Human: 100%
    产品特性
    This is a rabbit polyclonal antibody against A1CF. It was validated on Western Blot using a cell lysate as a positive control.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the N terminal region of human A1CF
    Top Product
    Discover our top product A1CF Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 594 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原
    A1CF (APOBEC1 Complementation Factor (A1CF))
    别名
    A1CF (A1CF 产品)
    别名
    ACF antibody, ACF64 antibody, ACF65 antibody, APOBEC1CF antibody, ASP antibody, 1810073H04Rik antibody, Acf antibody, A1cft antibody, Apobec-1 antibody, acf antibody, acf64 antibody, acf65 antibody, apobec1cf antibody, asp antibody, A1CF antibody, APOBEC1 complementation factor antibody, apobec1 complementation factor antibody, APOBEC1 complementation factor L homeolog antibody, A1CF antibody, A1cf antibody, a1cf antibody, a1cf.L antibody
    背景
    Mammalian apolipoprotein B mRNA undergoes site-specific C to U deamination, which is mediated by a multi-component enzyme complex containing a minimal core composed of APOBEC-1 and a complementation factor encoded by this gene. A1CF has three non-identical RNA recognition motifs and belongs to the hnRNP R family of RNA-binding proteins. It has been proposed that this complementation factor functions as an RNA-binding subunit and docks APOBEC-1 to deaminate the upstream cytidine. Studies suggest that the protein may also be involved in other RNA editing or RNA processing events. Alternative splicing occurs at this locus and three full-length transcript variants, encoding three distinct isoforms, have been described. Additional splicing has been observed but the full-length nature of these variants has not been determined.Mammalian apolipoprotein B mRNA undergoes site-specific C to U deamination, which is mediated by a multi-component enzyme complex containing a minimal core composed of APOBEC-1 and a complementation factor encoded by this gene. The gene product has three non-identical RNA recognition motifs and belongs to the hnRNP R family of RNA-binding proteins. It has been proposed that this complementation factor functions as an RNA-binding subunit and docks APOBEC-1 to deaminate the upstream cytidine. Studies suggest that the protein may also be involved in other RNA editing or RNA processing events. Alternative splicing occurs at this locus and three full-length transcript variants, encoding three distinct isoforms, have been described. Additional splicing has been observed but the full-length nature of these variants has not been determined.
    Alias Symbols: ACF, ACF64, ACF65, APOBEC1CF, ASP, MGC163391, RP11-564C4.2
    Protein Interaction Partner: SDPR, TRAF1, REL, FHL3, KHSRP, SYNCRIP, TNPO2, CELF2, APOBEC1,
    Protein Size: 594
    分子量
    65 kDa
    基因ID
    29974
    NCBI登录号
    NM_138933, NP_620311
    UniProt
    Q9NQ94
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