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A1CF 抗体 (N-Term)

This anti-A1CF antibody is a 兔 多克隆 antibody detecting A1CF in WB. Suitable for 人.
产品编号 ABIN2776627
发货至: 中国

Quick Overview for A1CF 抗体 (N-Term) (ABIN2776627)

抗原

See all A1CF 抗体
A1CF (APOBEC1 Complementation Factor (A1CF))

适用

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宿主

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克隆类型

  • 28
多克隆

标记

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This A1CF antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    N-Term

    序列

    EAVCLGTCPE PEASMSTAIP GLKKGNNALQ SIILQTLLEK ENGQRKYGGP

    预测反应

    Human: 100%

    产品特性

    This is a rabbit polyclonal antibody against A1CF. It was validated on Western Blot using a cell lysate as a positive control.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the N terminal region of human A1CF
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 594 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    A1CF (APOBEC1 Complementation Factor (A1CF))

    别名

    A1CF

    背景

    Mammalian apolipoprotein B mRNA undergoes site-specific C to U deamination, which is mediated by a multi-component enzyme complex containing a minimal core composed of APOBEC-1 and a complementation factor encoded by this gene. A1CF has three non-identical RNA recognition motifs and belongs to the hnRNP R family of RNA-binding proteins. It has been proposed that this complementation factor functions as an RNA-binding subunit and docks APOBEC-1 to deaminate the upstream cytidine. Studies suggest that the protein may also be involved in other RNA editing or RNA processing events. Alternative splicing occurs at this locus and three full-length transcript variants, encoding three distinct isoforms, have been described. Additional splicing has been observed but the full-length nature of these variants has not been determined.Mammalian apolipoprotein B mRNA undergoes site-specific C to U deamination, which is mediated by a multi-component enzyme complex containing a minimal core composed of APOBEC-1 and a complementation factor encoded by this gene. The gene product has three non-identical RNA recognition motifs and belongs to the hnRNP R family of RNA-binding proteins. It has been proposed that this complementation factor functions as an RNA-binding subunit and docks APOBEC-1 to deaminate the upstream cytidine. Studies suggest that the protein may also be involved in other RNA editing or RNA processing events. Alternative splicing occurs at this locus and three full-length transcript variants, encoding three distinct isoforms, have been described. Additional splicing has been observed but the full-length nature of these variants has not been determined.
    Alias Symbols: ACF, ACF64, ACF65, APOBEC1CF, ASP, MGC163391, RP11-564C4.2
    Protein Interaction Partner: SDPR, TRAF1, REL, FHL3, KHSRP, SYNCRIP, TNPO2, CELF2, APOBEC1,
    Protein Size: 594

    分子量

    65 kDa

    基因ID

    29974

    NCBI登录号

    NM_138933, NP_620311

    UniProt

    Q9NQ94
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