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EIF2A 抗体 (C-Term)

Cited in 3+ publications. This 兔 多克隆 anti-EIF2A antibody specifically detects EIF2A in WB 和 IHC. The antibody is reactive with 人, 小鼠, 大鼠, 犬, 马, 兔, Cow, 山羊, 豚鼠 和 斑马鱼 samples.
产品编号 ABIN2776588
发货至: 中国
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Quick Overview for EIF2A 抗体 (C-Term) (ABIN2776588)

抗原

See all EIF2A 抗体
EIF2A (Eukaryotic Translation Initiation Factor 2A, 65kDa (EIF2A))

适用

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人, 小鼠, 大鼠, 犬, 马, 兔, Cow, 山羊, 豚鼠, 斑马鱼

宿主

  • 98
  • 15
  • 2

克隆类型

  • 66
  • 49
多克隆

标记

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This EIF2A antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

    • 18
    • 17
    • 8
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    • 2
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    C-Term

    序列

    DKSPDLAPTP APQSTPRNTV SQSISGDPEI DKKIKNLKKK LKAIEQLKEQ

    预测反应

    Cow: 86%, Dog: 100%, Goat: 83%, Guinea Pig: 93%, Horse: 86%, Human: 100%, Mouse: 93%, Rabbit: 93%, Rat: 100%, Zebrafish: 93%

    产品特性

    This is a rabbit polyclonal antibody against EIF2A. It was validated on Western Blot and immunohistochemistry.

    纯化方法

    Protein A purified

    免疫原

    The immunogen is a synthetic peptide directed towards the C terminal region of human EIF2A
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 585 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Feng, Chen, Chan, Chen: "Therapeutic Role of Protein Tyrosine Phosphatase 1B in Parkinson's Disease via Antineuroinflammation and Neuroprotection In Vitro and In Vivo." in: Parkinson's disease, Vol. 2020, pp. 8814236, (2020) (PubMed).

    Xu, Liu, Caffaro, Hirschberg: "Inhibition of Golgi apparatus glycosylation causes endoplasmic reticulum stress and decreased protein synthesis." in: The Journal of biological chemistry, Vol. 285, Issue 32, pp. 24600-8, (2010) (PubMed).

    Su, Wang, Baltzis, Qu, Wong, Koromilas: "Tyrosine phosphorylation acts as a molecular switch to full-scale activation of the eIF2alpha RNA-dependent protein kinase." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 103, Issue 1, pp. 63-8, (2006) (PubMed).

  • 抗原

    EIF2A (Eukaryotic Translation Initiation Factor 2A, 65kDa (EIF2A))

    别名

    EIF2A

    背景

    EIF2A is a 65-kD protein that catalyzes the formation of puromycin-sensitive 80S preinitiation complexes.EIF2A is a 65-kD protein that catalyzes the formation of puromycin-sensitive 80S preinitiation complexes (Zoll et al., 2002).[supplied by OMIM].
    Alias Symbols: CDA02, MST089, MSTP004, MSTP089, EIF-2A
    Protein Interaction Partner: UBC, CDC20, RPS23, RPS19, RPS16, RPS10, RPS7, RPS5, HDLBP, PRUNE2, EIF3K, SERBP1, RPS29, RPS24, EIF2AK2, MLH1, NXF1, ILF3, PA2G4, APP, PPP1CC, NEDD8, DCC, ATF4,
    Protein Size: 585

    分子量

    64 kDa

    基因ID

    83939

    NCBI登录号

    NM_032025, NP_114414

    UniProt

    Q9BY44

    途径

    Ribonucleoprotein Complex Subunit Organization, ER-Nucleus Signaling, Hepatitis C, Methionine Biosynthetic Process, Ribosome Assembly
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