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TARDBP 抗体 (N-Term)

This 兔多克隆 antibody specifically detects TARDBP in WB 和 IHC. It exhibits reactivity toward 人, 小鼠, 大鼠, 斑马鱼, Cow, 犬, 马, 豚鼠和兔.

WB Suggested Anti-TARDBP Antibody Positive Control: Lane 1: 5ug mouse brain cytoplasm Lane 2: 5ug mouse brain nucleus Primary Antibody Dilution : 1:1000 Secondary Antibody : Anti rabbit - IR-dye Secondry Antibody Dilution : 1:10,000 Submitted by: Anonymous (TARDBP 抗体 (N-Term))

Rabbit Anti-TARDBP Antibody Catalog Number: ARP35838_P050 Formalin Fixed Paraffin Embedded Tissue: Human heart Tissue Observed Staining: Cytoplasmic Primary Antibody Concentration: 1:100 Other Working Concentrations: N/A Secondary Antibody: Donkey anti-Rabbit-Cy3 Secondary Antibody Concentration: 1:200 Magnification: 20X Exposure Time: 0. (TARDBP 抗体 (N-Term))

IHC

WB Suggested Anti-TARDBP Antibody Titration: 0. (TARDBP 抗体 (N-Term))

3 images

产品编号 ABIN2776487

发货至: 中国

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Quick Overview for TARDBP 抗体 (N-Term) (ABIN2776487)

抗原

See all TARDBP 抗体

TARDBP (TAR DNA Binding Protein (TARDBP))

适用

人, 小鼠, 大鼠, 斑马鱼, Cow, 犬, 马, 豚鼠, 兔

宿主

兔

克隆类型

多克隆

标记

This TARDBP antibody is un-conjugated

应用范围

Western Blotting (WB), Immunohistochemistry (IHC)

Discover our top product TARDBP Primary Antibody

抗原表位
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1
N-Term

原理

TARDBP Antibody - N-terminal region

序列

VYVVNYPKDN KRKMDETDAS SAVKVKRAVQ KTSDLIVLGL PWKTTEQDLK

预测反应

Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 77%

产品特性

This is a rabbit polyclonal antibody against TARDBP. It was validated on Western Blot using a cell lysate as a positive control.

纯化方法

Affinity Purified

免疫原

The immunogen is a synthetic peptide directed towards the N terminal region of human TARDBP
anti-TAR DNA Binding Protein (TARDBP) (AA 1-260) antibody
TARDBP 适用: 人 WB, IF, ELISA, IP, IHC (p), RNAi 宿主: 小鼠 Monoclonal 2E2-D3 unconjugated

anti-TAR DNA Binding Protein (TARDBP) antibody
TARDBP 适用: 人 WB, IHC, ELISA, ICC, FACS 宿主: 小鼠 Monoclonal 6G2D8 unconjugated

anti-TAR DNA Binding Protein (TARDBP) (AA 1-260) antibody
TARDBP 适用: 人 WB, IP, RIP 宿主: 兔 Polyclonal unconjugated

anti-TAR DNA Binding Protein (TARDBP) antibody
TARDBP 适用: 人 WB, IHC, IF 宿主: 兔 Monoclonal unconjugated

anti-TAR DNA Binding Protein (TARDBP) (AA 104-262) antibody
TARDBP 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-TAR DNA Binding Protein (TARDBP) (C-Term) antibody
TARDBP 适用: 人, 小鼠, 大鼠, Cow, 犬, 马, 豚鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-TAR DNA Binding Protein (TARDBP) (AA 1-100) antibody
TARDBP 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-TAR DNA Binding Protein (TARDBP) antibody
KD Validated TARDBP 适用: 人 WB, FACS, IF (p) 宿主: 兔 Monoclonal 23GB4730 unconjugated Recombinant Antibody

anti-TAR DNA Binding Protein (TARDBP) antibody
KO Validated TARDBP 适用: 人 WB, IF, ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-TAR DNA Binding Protein (TARDBP) (N-Term) antibody
TARDBP 适用: 人, 小鼠, 大鼠, Cow, 犬, 马, 豚鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated

应用备注

Optimal working dilution should be determined by the investigator.

说明

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP35838-100UG

限制

仅限研究用
状态

Liquid

浓度

0.5 mg/mL

缓冲液

Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

prevent freeze-thaw cycles

储存条件

4 °C,-20 °C

储存方法

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
抗原

TARDBP (TAR DNA Binding Protein (TARDBP))

别名

TARDBP

背景

Background Information: HIV-1, the causative agent of acquired immunodeficiency syndrome (AIDS), contains an RNA genome that produces a chromosomally integrated DNA during the replicative cycle. Activation of HIV-1 gene expression by the transactivator Tat is dependent on an RNA regulatory element (TAR) located downstream of the transcription initiation site. TARDBP is a transcriptional repressor that binds to chromosomally integrated TAR DNA and represses HIV-1 transcription.HIV-1, the causative agent of acquired immunodeficiency syndrome (AIDS), contains an RNA genome that produces a chromosomally integrated DNA during the replicative cycle. Activation of HIV-1 gene expression by the transactivator Tat is dependent on an RNA regulatory element (TAR) located downstream of the transcription initiation site. The protein encoded by this gene is a transcriptional repressor that binds to chromosomally integrated TAR DNA and represses HIV-1 transcription. In addition, this protein regulates alternate splicing of the CFTR gene. A similar pseudogene is present on chromosome 20. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Gene Name: TAR DNA binding protein
Alternative Symbols: ALS10, TDP-43
Protein Name: TAR DNA-binding protein 43

分子量

45kDa

基因ID

23435

NCBI登录号

NP_031401

UniProt

Q13148

途径

Positive Regulation of Peptide Hormone Secretion