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SSX4 抗体 (Middle Region)

SSX4 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2776446
发货至: 中国
  • 抗原 See all SSX4 抗体
    SSX4 (Synovial Sarcoma, X Breakpoint 4 (SSX4))
    抗原表位
    • 12
    • 12
    • 7
    • 7
    • 7
    • 6
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    适用
    • 44
    • 1
    • 1
    宿主
    • 40
    • 4
    克隆类型
    • 42
    • 2
    多克隆
    标记
    • 17
    • 5
    • 4
    • 4
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This SSX4 antibody is un-conjugated
    应用范围
    • 36
    • 28
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    序列
    FPKIMPKKPA EEENGLKEVP EASGPQNDGK QLCPPGNPST LEKINKTSGP
    预测反应
    Human: 100%
    产品特性
    This is a rabbit polyclonal antibody against SSX4. It was validated on Western Blot using a cell lysate as a positive control.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the middle region of human SSX4
    Top Product
    Discover our top product SSX4 Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 188 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原
    SSX4 (Synovial Sarcoma, X Breakpoint 4 (SSX4))
    别名
    SSX4 (SSX4 产品)
    别名
    CT5.4 antibody, SSX family member 4 antibody, SSX4 antibody
    背景
    SSX4 belongs to the SSX family. It contains 1 KRAB-related domain.SSX4 could act as a modulator of transcription. The product of this gene belongs to the family of highly homologous synovial sarcoma X (SSX) breakpoint proteins. These proteins may function as transcriptional repressors. They are also capable of eliciting spontaneously humoral and cellular immune responses in cancer patients, and are potentially useful targets in cancer vaccine-based immunotherapy. SSX1, SSX2 and SSX4 genes have been involved in the t(X,18) translocation characteristically found in all synovial sarcomas. This translocation results in the fusion of the synovial sarcoma translocation gene on chromosome 18 to one of the SSX genes on chromosome X. Chromosome Xp11 contains a segmental duplication resulting in two identical copies of synovial sarcoma, X breakpoint 4, SSX4 and SSX4B, in tail-to-tail orientation. This gene, SSX4, represents the more telomeric copy. Two transcript variants encoding distinct isoforms have been identified for this gene.
    Alias Symbols: MGC119056, MGC12411, CT5.4, SSX4B
    Protein Interaction Partner: LZTR1, XBP1, PAX9, HIF1A,
    Protein Size: 188
    分子量
    22 kDa
    基因ID
    6759
    NCBI登录号
    NM_005636, NP_005627
    UniProt
    O60224
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