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SSX4 抗体 (N-Term)

This anti-SSX4 antibody is a 兔 多克隆 antibody detecting SSX4 in WB. Suitable for 人 和 Cow.
产品编号 ABIN2776445
发货至: 中国

Quick Overview for SSX4 抗体 (N-Term) (ABIN2776445)

抗原

See all SSX4 抗体
SSX4 (Synovial Sarcoma, X Breakpoint 4 (SSX4))

适用

人, Cow

宿主

  • 27
  • 4

克隆类型

  • 29
  • 2
多克隆

标记

  • 14
  • 3
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This SSX4 antibody is un-conjugated

应用范围

  • 23
  • 18
  • 2
  • 1
  • 1
Western Blotting (WB)
  • 抗原表位

    • 7
    • 7
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term

    序列

    NGDDAFARRP RDDAQISEKL RKAFDDIAKY FSKKEWEKMK SSEKIVYVYM

    预测反应

    Cow: 83%, Human: 100%

    产品特性

    This is a rabbit polyclonal antibody against SSX4. It was validated on Western Blot using a cell lysate as a positive control.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the N terminal region of human SSX4
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 188 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    SSX4 (Synovial Sarcoma, X Breakpoint 4 (SSX4))

    别名

    SSX4

    背景

    SSX4 belongs to the SSX family. It contains 1 KRAB-related domain.SSX4 could act as a modulator of transcription. The product of this gene belongs to the family of highly homologous synovial sarcoma X (SSX) breakpoint proteins. These proteins may function as transcriptional repressors. They are also capable of eliciting spontaneously humoral and cellular immune responses in cancer patients, and are potentially useful targets in cancer vaccine-based immunotherapy. SSX1, SSX2 and SSX4 genes have been involved in the t(X,18) translocation characteristically found in all synovial sarcomas. This translocation results in the fusion of the synovial sarcoma translocation gene on chromosome 18 to one of the SSX genes on chromosome X. Chromosome Xp11 contains a segmental duplication resulting in two identical copies of synovial sarcoma, X breakpoint 4, SSX4 and SSX4B, in tail-to-tail orientation. This gene, SSX4, represents the more telomeric copy. Two transcript variants encoding distinct isoforms have been identified for this gene.
    Alias Symbols: MGC119056, MGC12411, CT5.4, SSX4B
    Protein Interaction Partner: LZTR1, XBP1, PAX9, HIF1A,
    Protein Size: 188

    分子量

    22 kDa

    基因ID

    6759

    NCBI登录号

    NM_005636, NP_005627

    UniProt

    O60224
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