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MTA2 抗体 (Middle Region)

MTA2 适用: 人, 小鼠, 大鼠, 犬, Cow, 马, 兔, 山羊, 豚鼠, Pig, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2776429
发货至: 中国
  • 抗原 See all MTA2 抗体
    MTA2 (Metastasis Associated 1 Family, Member 2 (MTA2))
    抗原表位
    • 7
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    适用
    • 44
    • 31
    • 28
    • 9
    • 8
    • 8
    • 8
    • 6
    • 6
    • 5
    • 5
    • 4
    • 4
    • 2
    • 1
    人, 小鼠, 大鼠, 犬, Cow, 马, 兔, 山羊, 豚鼠, Pig, 斑马鱼
    宿主
    • 43
    • 4
    克隆类型
    • 42
    • 5
    多克隆
    标记
    • 33
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This MTA2 antibody is un-conjugated
    应用范围
    • 47
    • 13
    • 10
    • 9
    • 7
    • 5
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    Western Blotting (WB)
    序列
    WKKYGGLKTP TQLEGATRGT TEPHSRGHLS RPEAQSLSPY TTSANRAKLL
    预测反应
    Cow: 93%, Dog: 93%, Goat: 93%, Guinea Pig: 86%, Horse: 93%, Human: 100%, Mouse: 93%, Pig: 93%, Rabbit: 93%, Rat: 93%, Zebrafish: 79%
    产品特性
    This is a rabbit polyclonal antibody against MTA2. It was validated on Western Blot using a cell lysate as a positive control.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the middle region of human MTA2
    Top Product
    Discover our top product MTA2 Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 668 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原
    MTA2 (Metastasis Associated 1 Family, Member 2 (MTA2))
    别名
    MTA2 (MTA2 产品)
    别名
    MTA1L1 antibody, PID antibody, fd61b05 antibody, wu:fd61b05 antibody, wu:fi29g02 antibody, zgc:63487 antibody, pid antibody, mta1l1 antibody, MTA2 antibody, DKFZp470E0911 antibody, AW550797 antibody, Mata1l1 antibody, Mta1l1 antibody, mmta2 antibody, metastasis associated 1 family member 2 antibody, metastasis associated 1 family, member 2 antibody, metastasis-associated gene family, member 2 antibody, metastasis associated 1 family member 2 L homeolog antibody, MTA2 antibody, mta2 antibody, Mta2 antibody, mta2.L antibody
    背景
    MTA2 has been identified as a component of NuRD, a nucleosome remodeling deacetylase complex identified in the nucleus of human cells. It shows a very broad expression pattern and is strongly expressed in many tissues. It may represent one member of a small gene family that encode different but related proteins involved either directly or indirectly in transcriptional regulation. Their indirect effects on transcriptional regulation may include chromatin remodeling.This gene encodes a protein that has been identified as a component of NuRD, a nucleosome remodeling deacetylase complex identified in the nucleus of human cells. It shows a very broad expression pattern and is strongly expressed in many tissues. It may represent one member of a small gene family that encode different but related proteins involved either directly or indirectly in transcriptional regulation. Their indirect effects on transcriptional regulation may include chromatin remodeling. It is closely related to another member of this family, a protein that has been correlated with the metastatic potential of certain carcinomas. These two proteins are so closely related that they share the same types of domains. These domains include two DNA binding domains, a dimerization domain, and a domain commonly found in proteins that methylate DNA. One of the proteins known to be a target protein for this gene product is p53. Deacteylation of p53 is correlated with a loss of growth inhibition in transformed cells supporting a connection between these gene family members and metastasis.This gene encodes a protein that has been identified as a component of NuRD, a nucleosome remodeling deacetylase complex identified in the nucleus of human cells. It shows a very broad expression pattern and is strongly expressed in many tissues. It may represent one member of a small gene family that encode different but related proteins involved either directly or indirectly in transcriptional regulation. Their indirect effects on transcriptional regulation may include chromatin remodeling. It is closely related to another member of this family, a protein that has been correlated with the metastatic potential of certain carcinomas. These two proteins are so closely related that they share the same types of domains. These domains include two DNA binding domains, a dimerization domain, and a domain commonly found in proteins that methylate DNA. One of the proteins known to be a target protein for this gene product is p53. Deacteylation of p53 is correlated with a loss of growth inhibition in transformed cells supporting a connection between these gene family members and metastasis. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
    Alias Symbols: DKFZp686F2281, MTA1L1, PID
    Protein Interaction Partner: vpr, SUMO2, SUMO3, DNMT3B, DNMT1, NACC2, ZBTB16, UBC, RARA, ZBTB1, RNF2, GPHN, HNRNPR, TRIM28, PPP4R1, ROCK2, SPAG9, POLR2C, POLR2A, MAP4, RPP25, LSM8, GET4, LARP7, CD2AP, NR3C1, MTOR, EHBP1L1, RABEP2, BRCC3, SMEK1, ZGPAT, HDAC1, HDAC2, CSNK1E, MTA3, UBE3
    Protein Size: 668
    分子量
    75 kDa
    基因ID
    9219
    NCBI登录号
    NM_004739, NP_004730
    UniProt
    O94776
    途径
    Chromatin Binding
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