DMP1 抗体 (Middle Region)
Quick Overview for DMP1 抗体 (Middle Region) (ABIN2776044)
抗原
See all DMP1 (DMTF1) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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序列
- TFPDEIHHPK MTVEPSFNDA HVSKFSDQNS TELMNSVMVR TEEEISDTDL
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预测反应
- Cow: 93%, Dog: 93%, Guinea Pig: 92%, Horse: 100%, Human: 100%, Mouse: 93%, Pig: 93%, Rabbit: 93%, Rat: 86%
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产品特性
- This is a rabbit polyclonal antibody against DMTF1. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human DMTF1
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anti-Cyclin D Binding Myb-Like Transcription Factor 1 (DMTF1) (AA 661-760) antibody
DMTF1 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 5C6 unconjugated
anti-Cyclin D Binding Myb-Like Transcription Factor 1 (DMTF1) (AA 221-330) antibodyDMTF1 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 1D4 unconjugated
anti-Cyclin D Binding Myb-Like Transcription Factor 1 (DMTF1) (C-Term) antibodyDMTF1 适用: 人, 小鼠, 大鼠, 犬, 马, 兔, 豚鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Cyclin D Binding Myb-Like Transcription Factor 1 (DMTF1) (AA 254-513) antibodyDMTF1 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Cyclin D Binding Myb-Like Transcription Factor 1 (DMTF1) (AA 626-675) antibodyDMTF1 适用: 人, Pig, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Cyclin D Binding Myb-Like Transcription Factor 1 (DMTF1) (AA 661-760) antibodyDMTF1 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Cyclin D Binding Myb-Like Transcription Factor 1 (DMTF1) (Internal Region) antibodyVerified DMTF1 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Cyclin D Binding Myb-Like Transcription Factor 1 (DMTF1) (AA 629-642) antibodyVerified DMTF1 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Cyclin D Binding Myb-Like Transcription Factor 1 (DMTF1) (N-Term) antibodyVerified DMTF1 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 760 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- DMP1 (DMTF1) (Cyclin D Binding Myb-Like Transcription Factor 1 (DMTF1))
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别名
- DMTF1
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背景
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DMTF1 is a transcription factor that contains a cyclin D-binding domain, three central Myb-like repeats, and two flanking acidic transactivation domains at the N- and C-termini. DMTF1 is induced by the oncogenic Ras signaling pathway and functions as a tumor suppressor by activating the transcription of ARF and thus the ARF-p53 pathway to arrest cell growth or induce apoptosis. It also activates the transcription of aminopeptidase N and may play a role in hematopoietic cell differentiation. The transcriptional activity of DMTF1 is regulated by binding of D-cyclins. The gene encoding DMTF1 is hemizygously deleted in approximately 40 % of human non-small-cell lung cancer and is a potential prognostic and gene-therapy target for non-small-cell lung cancer.
Alias Symbols: DMP1, DMTF, FLJ41265, hDMP1
Protein Interaction Partner: SRA1, TP53, ATF7IP, CCND1, CCND3, CCND2,
Protein Size: 760 -
分子量
- 84 kDa
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基因ID
- 9988
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NCBI登录号
- NM_021145, NP_066968
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UniProt
- Q9Y222
抗原
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