PHD1 抗体 (N-Term)
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北京 101111
Quick Overview for PHD1 抗体 (N-Term) (ABIN2775992)
抗原
See all PHD1 (EGLN2) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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原理
- EGLN2 Antibody - N-terminal region
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序列
- MCLPSPSKPT SLHPCQAMVA CYPGNGLGYV RHVDNPHGDG RCITCIYYLN
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预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 86%, Zebrafish: 93%
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产品特性
- This is a rabbit polyclonal antibody against EGLN2. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human EGLN2
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anti-Egl-9 Family Hypoxia Inducible Factor 2 (EGLN2) (AA 194-221) antibody
EGLN2 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB22708 unconjugated
anti-Egl-9 Family Hypoxia Inducible Factor 2 (EGLN2) (AA 58-107) antibodyEGLN2 适用: 人, Cow, 豚鼠 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Egl-9 Family Hypoxia Inducible Factor 2 (EGLN2) (AA 150-250) antibodyEGLN2 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Egl-9 Family Hypoxia Inducible Factor 2 (EGLN2) (AA 283-407) antibodyEGLN2 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Egl-9 Family Hypoxia Inducible Factor 2 (EGLN2) antibodyEGLN2 适用: 人 WB, FACS 宿主: 兔 Monoclonal 24GB3910 unconjugated Recombinant Antibody
anti-Egl-9 Family Hypoxia Inducible Factor 2 (EGLN2) (AA 1-407) antibodyEGLN2 适用: 人 ELISA 宿主: 小鼠 Monoclonal 2G3 unconjugated
anti-Egl-9 Family Hypoxia Inducible Factor 2 (EGLN2) (C-Term) antibodyEGLN2 适用: 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Egl-9 Family Hypoxia Inducible Factor 2 (EGLN2) (AA 281-315) antibodyEGLN2 适用: 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 兔, 马, Pig, 猴, Bat WB 宿主: 兔 Polyclonal unconjugated
anti-Egl-9 Family Hypoxia Inducible Factor 2 (EGLN2) (N-Term) antibodyEGLN2 适用: 人, 小鼠, 大鼠, 犬 WB 宿主: 兔 Polyclonal unconjugated
anti-Egl-9 Family Hypoxia Inducible Factor 2 (EGLN2) (C-Term) antibodyEGLN2 适用: 人, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP34747-100UG
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 mg/mL
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缓冲液
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- prevent freeze-thaw cycles
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储存条件
- 4 °C,-20 °C
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储存方法
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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: "Exercise training attenuates placental ischemia-induced hypertension and angiogenic imbalance in the rat." in: Hypertension, Vol. 60, Issue 6, pp. 1545-51, (2012) (PubMed).
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- PHD1 (EGLN2) (Egl-9 Family Hypoxia Inducible Factor 2 (EGLN2))
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别名
- EGLN2
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背景
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Background Information: The hypoxia inducible factor (HIF) is a transcriptional complex which is involved in oxygen homeostasis. At normal oxygen levels, the alpha subunit of HIF is targeted for degration by prolyl hydroxylation. EGLN2 encodes an enzyme responsible for this posttranslational modification. Alternative splicing of EGLN2 results in three transcript variants encoding different isoforms.
Gene Name: Egl nine homolog 2 (C. elegans)
Alternative Symbols: EIT6, PHD1, EIT-6, HPH-1, HPH-3, HIFPH1, HIF-PH1
Protein Name: Egl nine homolog 2
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分子量
- 16kDa
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基因ID
- 112398
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UniProt
- Q96KS0
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途径
- Intracellular Steroid Hormone Receptor Signaling Pathway, Cell RedoxHomeostasis
抗原
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