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LIN28A 抗体 (N-Term)

This anti-LIN28A antibody is a 兔 多克隆 antibody detecting LIN28A in WB 和 IHC. Suitable for 人, 小鼠, 大鼠, Cow, 犬, Pig, 绵羊, 山羊, 豚鼠, 兔 和 Saccharomyces cerevisiae.
产品编号 ABIN2775818
发货至: 中国

Quick Overview for LIN28A 抗体 (N-Term) (ABIN2775818)

抗原

See all LIN28A 抗体
LIN28A (Lin-28 Homolog A (C. Elegans) (LIN28A))

适用

人, 小鼠, 大鼠, Cow, 犬, Pig, 绵羊, 山羊, 豚鼠, 兔, Saccharomyces cerevisiae

宿主

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克隆类型

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多克隆

标记

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This LIN28A antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

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    N-Term

    序列

    GSVSNQQFAG GCAKAAEEAP EEAPEDAARA ADEPQLLHGA GICKWFNVRM

    预测反应

    Cow: 100%, Dog: 100%, Goat: 91%, Guinea Pig: 86%, Human: 100%, Mouse: 90%, Pig: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Yeast: 77%

    产品特性

    This is a rabbit polyclonal antibody against LIN28. It was validated on Western Blot using a cell lysate as a positive control.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the N terminal region of human LIN28
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 209 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    LIN28A (Lin-28 Homolog A (C. Elegans) (LIN28A))

    别名

    LIN28

    背景

    LIN28 acts as a 'translational enhancer', driving specific mRNAs to polysomes and thus increasing the efficiency of protein synthesis. The association of LIN28 with the translational machinery and target mRNAs results in an increased number of initiation events per molecule of mRNA and, indirectly, in stabilizing the mRNAs. IT binds IGF2 mRNA, MYOD1 mRNA, ARBP/36B4 ribosomal protein mRNA and its own mRNA. LIN28 is Essential for skeletal muscle differentiation program through the translational up-regulation of IGF2 expression.
    Alias Symbols: CSDD1, FLJ12457, LIN-28, LIN28A, ZCCHC1, LIN28, lin-28A
    Protein Interaction Partner: HNRNPUL2, HNRNPA3, DHX36, SREK1, TRIM71, LARP4, TGS1, DHX57, GADD45GIP1, LTV1, NOA1, DDX50, KRI1, NOL6, METTL17, NOC3L, ZC3HAV1, PPAN, CCBL2, MEPCE, TSR1, NHP2, NOP10, STRBP, BRIX1, RBM28, PHAX, SRRT, LARP7, DDX41, HP1BP3, NOB1, PRPF19, ZBTB11, SND1, AATF
    Protein Size: 209

    分子量

    23 kDa

    基因ID

    79727

    NCBI登录号

    NM_024674, NP_078950

    UniProt

    Q9H9Z2

    途径

    Stem Cell Maintenance
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