LIN28A 抗体 (N-Term)
Quick Overview for LIN28A 抗体 (N-Term) (ABIN2775818)
抗原
See all LIN28A 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- N-Term
-
序列
- GSVSNQQFAG GCAKAAEEAP EEAPEDAARA ADEPQLLHGA GICKWFNVRM
-
预测反应
- Cow: 100%, Dog: 100%, Goat: 91%, Guinea Pig: 86%, Human: 100%, Mouse: 90%, Pig: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Yeast: 77%
-
产品特性
- This is a rabbit polyclonal antibody against LIN28. It was validated on Western Blot using a cell lysate as a positive control.
-
纯化方法
- Affinity Purified
-
免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human LIN28
-
-
-
-
应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
-
说明
-
Antigen size: 209 AA
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- Lot specific
-
缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- Avoid repeated freeze-thaw cycles.
-
储存条件
- -20 °C
-
储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
-
-
- LIN28A (Lin-28 Homolog A (C. Elegans) (LIN28A))
-
别名
- LIN28
-
背景
-
LIN28 acts as a 'translational enhancer', driving specific mRNAs to polysomes and thus increasing the efficiency of protein synthesis. The association of LIN28 with the translational machinery and target mRNAs results in an increased number of initiation events per molecule of mRNA and, indirectly, in stabilizing the mRNAs. IT binds IGF2 mRNA, MYOD1 mRNA, ARBP/36B4 ribosomal protein mRNA and its own mRNA. LIN28 is Essential for skeletal muscle differentiation program through the translational up-regulation of IGF2 expression.
Alias Symbols: CSDD1, FLJ12457, LIN-28, LIN28A, ZCCHC1, LIN28, lin-28A
Protein Interaction Partner: HNRNPUL2, HNRNPA3, DHX36, SREK1, TRIM71, LARP4, TGS1, DHX57, GADD45GIP1, LTV1, NOA1, DDX50, KRI1, NOL6, METTL17, NOC3L, ZC3HAV1, PPAN, CCBL2, MEPCE, TSR1, NHP2, NOP10, STRBP, BRIX1, RBM28, PHAX, SRRT, LARP7, DDX41, HP1BP3, NOB1, PRPF19, ZBTB11, SND1, AATF
Protein Size: 209 -
分子量
- 23 kDa
-
基因ID
- 79727
-
NCBI登录号
- NM_024674, NP_078950
-
UniProt
- Q9H9Z2
-
途径
- Stem Cell Maintenance
抗原
-