ZYX 抗体 (Middle Region)
Quick Overview for ZYX 抗体 (Middle Region) (ABIN2775767)
抗原
See all ZYX 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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序列
- QPRGPPASSP APAPKFSPVT PKFTPVASKF SPGAPGGSGS QPNQKLGHPE
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预测反应
- Cow: 86%, Dog: 93%, Guinea Pig: 86%, Horse: 93%, Human: 100%, Rabbit: 79%, Rat: 86%
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产品特性
- This is a rabbit polyclonal antibody against ZYX. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human ZYX
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anti-Zyxin (ZYX) (AA 1-572) antibody
ZYX 适用: 人 WB, ELISA, IF, IP, RNAi 宿主: 小鼠 Monoclonal 2C10-4A7 unconjugated
anti-Zyxin (ZYX) (Internal Region) antibodyZYX 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Zyxin (ZYX) (AA 1-572) antibodyZYX 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 2D1 unconjugated
anti-Zyxin (ZYX) antibodyZYX 适用: 人, 小鼠, 大鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Zyxin (ZYX) (AA 1-300) antibodyZYX 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Zyxin (ZYX) (AA 1-573) antibodyZYX 适用: 人, 小鼠 WB, IHC, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 2D1 unconjugated
anti-Zyxin (ZYX) (AA 1-572) antibodyZYX 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Zyxin (ZYX) (Middle Region) antibodyZYX 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔 WB 宿主: 兔 Polyclonal unconjugated
anti-Zyxin (ZYX) (AA 352-357) antibodyZYX 适用: 人, 小鼠, 大鼠, Hamster WB, IP, ICC 宿主: 小鼠 Monoclonal 164D4 unconjugated
anti-Zyxin (ZYX) (AA 1-572) antibodyZYX 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 572 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- ZYX (Zyxin (ZYX))
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别名
- ZYX
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背景
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TRIM50 is an E3 ubiquitin-protein ligase.Focal adhesions are actin-rich structures that enable cells to adhere to the extracellular matrix and at which protein complexes involved in signal transduction assemble. Zyxin is a zinc-binding phosphoprotein that concentrates at focal adhesions and along the actin cytoskeleton. Zyxin has an N-terminal proline-rich domain and three LIM domains in its C-terminal half. The proline-rich domain may interact with SH3 domains of proteins involved in signal transduction pathways while the LIM domains are likely involved in protein-protein binding. Zyxin may function as a messenger in the signal transduction pathway that mediates adhesion-stimulated changes in gene expression and may modulate the cytoskeletal organization of actin bundles. Alternative splicing results in multiple transcript variants that encode the same isoform.
Alias Symbols: ESP-2, HED-2
Protein Interaction Partner: RTN4IP1, YPEL3, IMP3, PHF21A, PDLIM5, LIN7A, SUMO1, NEDD8, FAM129B, CORO1B, CAND1, PUF60, PAPOLA, NUDC, SEC23B, SEC24C, HIST1H4A, UGP2, TARS, PXN, GART, GARS, APEH, FN1, HIPK3, VCAM1, UBC, UBL7, UFC1, UBXN7, ZC3H7B, TTLL12, FERMT2, TOMM34, AHCYL1, SSSCA1,
Protein Size: 572 -
分子量
- 61 kDa
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基因ID
- 7791
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NCBI登录号
- NM_003461, NP_003452
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UniProt
- Q15942
抗原
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