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UBE2M 抗体 (N-Term)

Cited in 1 publication. This anti-UBE2M antibody is a 兔 多克隆 antibody detecting UBE2M in WB 和 IHC. Suitable for 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 马 和 兔.
产品编号 ABIN2775686
发货至: 中国
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Quick Overview for UBE2M 抗体 (N-Term) (ABIN2775686)

抗原

See all UBE2M (ube2m) 抗体
UBE2M (ube2m) (Ubiquitin-Conjugating Enzyme E2M (ube2m))

适用

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人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 马, 兔

宿主

  • 35
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克隆类型

  • 33
  • 5
多克隆

标记

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This UBE2M antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

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    N-Term

    序列

    IKLFSLKQQK KEEESAGGTK GSSKKASAAQ LRIQKDINEL NLPKTCDISF

    预测反应

    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

    产品特性

    This is a rabbit polyclonal antibody against UBE2M. It was validated on Western Blot using a cell lysate as a positive control.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the N terminal region of human UBE2M
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 183 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Ewing, Chu, Elisma, Li, Taylor, Climie, McBroom-Cerajewski, Robinson, OConnor, Li, Taylor, Dharsee, Ho, Heilbut, Moore, Zhang, Ornatsky, Bukhman, Ethier, Sheng, Vasilescu, Abu-Farha, Lambert, Duewel et al.: "Large-scale mapping of human protein-protein interactions by mass spectrometry. ..." in: Molecular systems biology, Vol. 3, pp. 89, (2007) (PubMed).

  • 抗原

    UBE2M (ube2m) (Ubiquitin-Conjugating Enzyme E2M (ube2m))

    别名

    UBE2M

    背景

    The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. UBE2M is a member of the E2 ubiquitin-conjugating enzyme family. It is linked with a ubiquitin-like protein, NEDD8, which can be conjugated to cellular proteins, such as Cdc53/culin.The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. The encoded protein is linked with a ubiquitin-like protein, NEDD8, which can be conjugated to cellular proteins, such as Cdc53/culin.
    Alias Symbols: UBC-RS2, UBC12, hUbc12
    Protein Interaction Partner: DCUN1D1, DCUN1D4, RBX1, UBC, MARCH7, UBE2M, CUL1, DCUN1D3, SMURF1, CAND1, DCUN1D2, NEDD8, DCUN1D5, LMNA, VCAM1, ITGA4, FN1, VCP, UBE2D2, TYMS, TST, VAMP2, PARK2, PINK1, UBE2T, SEC22B, SLC9A3R2, APP, CUL3, CUL4A, TP53, UBD, COPS6, UBA3, NAE1, CUL2, Nedd4,
    Protein Size: 183

    分子量

    21 kDa

    基因ID

    9040

    NCBI登录号

    NM_003969, NP_003960

    UniProt

    P61081
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