UBE2D1 抗体 (Middle Region)
Quick Overview for UBE2D1 抗体 (Middle Region) (ABIN2775671)
抗原
See all UBE2D1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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序列
- SQWSPALTVS KVLLSICSLL CDPNPDDPLV PDIAQIYKSD KEKYNRHARE
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预测反应
- Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 79%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 93%, Rat: 100%, Zebrafish: 93%
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产品特性
- This is a rabbit polyclonal antibody against UBE2D1. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Protein A purified
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免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human UBE2D1
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anti-Ubiquitin-Conjugating Enzyme E2D 1 (UBE2D1) (AA 1-94) antibody
UBE2D1 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 2C6 unconjugated
anti-Ubiquitin-Conjugating Enzyme E2D 1 (UBE2D1) antibodyUBE2D1 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin-Conjugating Enzyme E2D 1 (UBE2D1) (AA 1-147) antibodyUBE2D1 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin-Conjugating Enzyme E2D 1 (UBE2D1) (AA 1-95) antibodyUBE2D1 适用: 人 WB, IHC, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 2C6 unconjugated
anti-Ubiquitin-Conjugating Enzyme E2D 1 (UBE2D1) (C-Term) antibodyUBE2D1 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin-Conjugating Enzyme E2D 1 (UBE2D1) (AA 111-140), (C-Term) antibodyUBE2D1 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB04139 unconjugated
anti-Ubiquitin-Conjugating Enzyme E2D 1 (UBE2D1) (AA 91-140) antibodyUBE2D1 适用: 人, 小鼠, 大鼠, 犬, Cow, 山羊, 马, Pig, Bat, 小鸡, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin-Conjugating Enzyme E2D 1 (UBE2D1) antibodyUBE2D1 适用: 人, 小鼠, 大鼠, 犬 WB 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin-Conjugating Enzyme E2D 1 (UBE2D1) (C-Term) antibodyUBE2D1 适用: 人, 小鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 147 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- UBE2D1 (Ubiquitin-Conjugating Enzyme E2D 1 (UBE2D1))
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别名
- UBE2D1
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背景
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The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. UBE2D1 is a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is closely related to a stimulator of iron transport (SFT), and is up-regulated in hereditary hemochromatosis. It also functions in the ubiquitination of the tumor-suppressor protein p53 and the hypoxia-inducible transcription factor HIF1alpha by interacting with the E1 ubiquitin-activating enzyme and the E3 ubiquitin-protein ligases.
Alias Symbols: E2(17)KB1, SFT, UBC4/5, UBCH5, UBCH5A
Protein Interaction Partner: RBX1, STUB1, RNF7, RNF14, MID1, MDM2, EP300, CREBBP, ANAPC11, DTL, RNF115, MKRN2, NEDD4L, FAF2, TRIM32, MID2, RNF111, RNF5, RSP5, GPB1, NHLRC1, RFFL, UHRF2, DTX2, ZNRF1, TRIM63, RNF146, FBXO31, RNF26, TRIM39, RNF126, FBXW7, NEDD4, CUL1, CUL3, MKRN3, UBE3A
Protein Size: 147 -
分子量
- 16 kDa
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基因ID
- 7321
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NCBI登录号
- NM_001204880, NP_003329
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UniProt
- P51668
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途径
- Activation of Innate immune Response, Toll-Like Receptors Cascades
抗原
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