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RFFL 抗体 (Middle Region)

RFFL 适用: 人, 小鼠, 大鼠, Cow, 马, 犬, 兔, 豚鼠 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2775666
发货至: 中国
  • 抗原 See all RFFL 抗体
    RFFL (Ring Finger and FYVE-Like Domain Containing 1 (RFFL))
    抗原表位
    • 15
    • 14
    • 7
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Middle Region
    适用
    • 41
    • 21
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    人, 小鼠, 大鼠, Cow, 马, 犬, 兔, 豚鼠
    宿主
    • 38
    • 3
    克隆类型
    • 39
    • 2
    多克隆
    标记
    • 17
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This RFFL antibody is un-conjugated
    应用范围
    • 39
    • 22
    • 13
    • 13
    • 3
    • 3
    • 3
    • 1
    Western Blotting (WB)
    序列
    KDQKGLQHLV SGAEDQNGGA VPSGLEENLC KICMDSPIDC VLLECGHMVT
    预测反应
    Cow: 93%, Dog: 93%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%
    产品特性
    This is a rabbit polyclonal antibody against RFFL. It was validated on Western Blot using a cell lysate as a positive control.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the middle region of human RFFL
    Top Product
    Discover our top product RFFL Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 363 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Hanuszkiewicz, Pittock, Humphries, Moll, Rosales, Molinaro, Moynagh, Lajoie, Valvano: "Identification of the flagellin glycosylation system in Burkholderia cenocepacia and the contribution of glycosylated flagellin to evasion of human innate immune responses." in: The Journal of biological chemistry, Vol. 289, Issue 27, pp. 19231-44, (2014) (PubMed).

  • 抗原
    RFFL (Ring Finger and FYVE-Like Domain Containing 1 (RFFL))
    别名
    RFFL (RFFL 产品)
    别名
    MGC84042 antibody, RFFL antibody, Rffl antibody, 1700051E09Rik antibody, 4930516L10Rik antibody, BG080975 antibody, Carp2 antibody, CARP-2 antibody, CARP2 antibody, FRING antibody, RIFIFYLIN antibody, RNF189 antibody, RNF34L antibody, ring finger and FYVE like domain containing E3 ubiquitin protein ligase antibody, ring finger and FYVE-like domain containing E3 ubiquitin protein ligase L homeolog antibody, ring finger and FYVE-like domain containing 1 antibody, ring finger and FYVE like domain containing protein antibody, ring finger and FYVE-like domain containing E3 ubiquitin protein ligase antibody, RFFL antibody, rffl.L antibody, Rffl antibody
    背景
    RFFL has E3 ubiquitin protein ligase activity.RFFL regulates the levels of CASP8 and CASP10 by targeting them for proteasomal degradation. Has anti-apoptotic activity.RFFL may bind phosphatidylinositol phosphates.
    Alias Symbols: RNF189, RNF34L, CARP2, FRING, CARP-2, RIFIFYLIN
    Protein Interaction Partner: RIPK1, UBE2D1, UBC, UBE2D2, RFFL, ATXN3L, OTUB2, USP28, OTUB1, UCHL5, ESPL1, USP5, STAM, USP7, UBE2D3, ATXN3, TP53, MDM2, UBE2G2,
    Protein Size: 363
    分子量
    40 kDa
    基因ID
    117584
    NCBI登录号
    NM_001017368, NP_001017368
    UniProt
    Q8WZ73
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