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RFFL 抗体 (Middle Region)

Cited in 1 publication. This 兔 多克隆 anti-RFFL antibody specifically detects RFFL in WB. The antibody is reactive with 人, 小鼠, 大鼠, Cow, 马, 犬, 兔 和 豚鼠 samples.
产品编号 ABIN2775666
发货至: 中国
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Quick Overview for RFFL 抗体 (Middle Region) (ABIN2775666)

抗原

See all RFFL 抗体
RFFL (Ring Finger and FYVE-Like Domain Containing 1 (RFFL))

适用

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人, 小鼠, 大鼠, Cow, 马, 犬, 兔, 豚鼠

宿主

  • 37
  • 3

克隆类型

  • 38
  • 2
多克隆

标记

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This RFFL antibody is un-conjugated

应用范围

  • 32
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Western Blotting (WB)
  • 抗原表位

    • 15
    • 9
    • 2
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    • 1
    • 1
    • 1
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    Middle Region

    序列

    KDQKGLQHLV SGAEDQNGGA VPSGLEENLC KICMDSPIDC VLLECGHMVT

    预测反应

    Cow: 93%, Dog: 93%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

    产品特性

    This is a rabbit polyclonal antibody against RFFL. It was validated on Western Blot using a cell lysate as a positive control.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the middle region of human RFFL
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 363 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Hanuszkiewicz, Pittock, Humphries, Moll, Rosales, Molinaro, Moynagh, Lajoie, Valvano: "Identification of the flagellin glycosylation system in Burkholderia cenocepacia and the contribution of glycosylated flagellin to evasion of human innate immune responses." in: The Journal of biological chemistry, Vol. 289, Issue 27, pp. 19231-44, (2014) (PubMed).

  • 抗原

    RFFL (Ring Finger and FYVE-Like Domain Containing 1 (RFFL))

    别名

    RFFL

    背景

    RFFL has E3 ubiquitin protein ligase activity.RFFL regulates the levels of CASP8 and CASP10 by targeting them for proteasomal degradation. Has anti-apoptotic activity.RFFL may bind phosphatidylinositol phosphates.
    Alias Symbols: RNF189, RNF34L, CARP2, FRING, CARP-2, RIFIFYLIN
    Protein Interaction Partner: RIPK1, UBE2D1, UBC, UBE2D2, RFFL, ATXN3L, OTUB2, USP28, OTUB1, UCHL5, ESPL1, USP5, STAM, USP7, UBE2D3, ATXN3, TP53, MDM2, UBE2G2,
    Protein Size: 363

    分子量

    40 kDa

    基因ID

    117584

    NCBI登录号

    NM_001017368, NP_001017368

    UniProt

    Q8WZ73
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