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HDAC9 抗体 (Middle Region)

This anti-HDAC9 antibody is a 兔 多克隆 antibody detecting HDAC9 in WB. Suitable for 人, 大鼠, 小鼠, 犬, 豚鼠, 绵羊, Cow, 马, 兔 和 斑马鱼. This Primary Antibody has been cited in 1 publication.
产品编号 ABIN2775579
发货至: 中国

Quick Overview for HDAC9 抗体 (Middle Region) (ABIN2775579)

抗原

See all HDAC9 抗体
HDAC9 (Histone Deacetylase 9 (HDAC9))

适用

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  • 1
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人, 大鼠, 小鼠, 犬, 豚鼠, 绵羊, Cow, 马, 兔, 斑马鱼

宿主

  • 70
  • 10

克隆类型

  • 61
  • 19
多克隆

标记

  • 52
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This HDAC9 antibody is un-conjugated

应用范围

  • 59
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  • 13
  • 8
  • 3
  • 2
  • 1
  • 1
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Western Blotting (WB)
  • 抗原表位

    • 13
    • 9
    • 8
    • 5
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    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
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    • 1
    • 1
    • 1
    Middle Region

    序列

    GQVGAVKVKE EPVDSDEDAQ IQEMESGEQA AFMQQVIGKD LAPGFVIKVI

    预测反应

    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%, Sheep: 100%, Zebrafish: 100%

    产品特性

    This is a rabbit polyclonal antibody against HDAC9. It was validated on Western Blot using a cell lysate as a positive control.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the middle region of human HDAC9
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 590 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Su, Becker, Kozyrskyj, Hayglass: "Epigenetic regulation of established human type 1 versus type 2 cytokine responses." in: The Journal of allergy and clinical immunology, Vol. 121, Issue 1, pp. 57-63.e3, (2008) (PubMed).

  • 抗原

    HDAC9 (Histone Deacetylase 9 (HDAC9))

    别名

    HDAC9

    背景

    Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. HDAC9 has sequence homology to members of the histone deacetylase family. The MITR protein lacks the histone deacetylase catalytic domain. It represses MEF2 activity through recruitment of multicomponent corepressor complexes that include CtBP and HDACs. HDAC9 may play a role in hematopoiesis. Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene has sequence homology to members of the histone deacetylase family. This gene is orthologous to the Xenopus and mouse MITR genes. The MITR protein lacks the histone deacetylase catalytic domain. It represses MEF2 activity through recruitment of multicomponent corepressor complexes that include CtBP and HDACs. This encoded protein may play a role in hematopoiesis. Multiple alternatively spliced transcripts have been described for this gene but the full-length nature of some of them has not been determined.
    Alias Symbols: DKFZp779K1053, HD7, HDAC, HDAC7, HDAC7B, HDAC9B, HDAC9FL, HDRP, KIAA0744, MITR, HD9, HD7b
    Protein Interaction Partner: NOP2, MKI67, EIF6, RCC1, ADAR, TOP1, TMPO, FIP1L1, CCAR2, TPX2, RBM14, ZC3H11A, HDAC9, NUP93, SMC3, H1FX, TPR, HINT1, CTBP1, BCL6, Zfp521, TRIM29, TP53, MAML1, SMARCA4, PARP1, CEBPB, H3F3A, RL2, CAMK1, YWHAE, HDAC1, SFN, MEF2B, ANKRA2, RFXANK, PKD1, SYK,
    Protein Size: 590

    分子量

    66 kDa

    基因ID

    9734

    NCBI登录号

    NM_014707, NP_055522

    UniProt

    A7E2F3

    途径

    Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development
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